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FNTB protein, human

Known as: CAAX Box Farnesyltransferase Beta, Protein Farnesyltransferase Beta Subunit, CAAX Box Farnesyltransferase Beta Subunit 
Protein farnesyltransferase subunit beta (437 aa, ~49 kDa) is encoded by the human FNTB gene. This protein plays a role in protein farnesylation.
National Institutes of Health

Related topics

Related topics

7 relations
Enzyme GeneFNTB geneFNTB wt AlleleProtein Complex Subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Rce1 suppresses invasion and metastasis of hepatocellular carcinoma via epithelial‐mesenchymal transition induced by the TGF‐β1/H‐Ras signaling pathway
Ras converting enzyme 1 (Rce1) plays an important role in invasion and metastasis of malignancy. However, the mechanism has not… 
2020
2020
Combining mutagenesis on Glu281 of prenyltransferase NovQ and metabolic engineering strategies for the increased prenylated activity towards menadione
Prenyltransferase NovQ is a vital class involved in the biosynthesis of secondary metabolites such as clorobiocin and novobiocin… 
2014
2014
The regulator of G protein signaling (RGS) domain of G protein–coupled receptor kinase 5 (GRK5) regulates plasma membrane localization and function
GRK5/GRK4 chimeras and point mutations in GRK5 identify a short sequence within the RGS domain in GRK5 that is critical for GRK5… 
Highly Cited
2011
Highly Cited
2011
Splice variant–specific cellular function of the formin INF2 in maintenance of Golgi architecture
INF2 is a unique formin that can both polymerize and depolymerize actin. One INF2 splice variant localizes in an actin-dependent… 
2011
2011
Computational analysis of the fructosyltransferase enzymes in plants, fungi and bacteria.
2011
2011
FPTB, a novel CA‐4 derivative, induces cell apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress pathways
Chondrosarcoma is a malignant primary bone tumor that responds poorly to both chemotherapy and radiation therapy. The aim of this… 
Highly Cited
2006
Highly Cited
2006
Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation
ABSTRACT Like other small G proteins of the Ras superfamily, Rap1 is activated by distinct guanine nucleotide exchange factors… 
Highly Cited
2002
Highly Cited
2002
Socius Is a Novel Rnd GTPase-Interacting Protein Involved in Disassembly of Actin Stress Fibers
ABSTRACT Rho family small GTPases are key regulators of the actin cytoskeleton in various cell types. The Rnd proteins, Rnd1… 
1997
1997
Synthesis and biological activity of semipeptoid farnesyltransferase inhibitors.
1993
1993
Protein Farnesyltransferase in Plants (Molecular Cloning and Expression of a Homolog of the [beta] Subunit from the Garden Pea)
Protein farnesyltransferase is a heterodimeric enzyme that attaches a farnesyl moiety to C-terminal cysteine residues. Both the… 
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