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FNTB protein, human

Known as: CAAX Box Farnesyltransferase Beta, Protein Farnesyltransferase Beta Subunit, CAAX Box Farnesyltransferase Beta Subunit 
Protein farnesyltransferase subunit beta (437 aa, ~49 kDa) is encoded by the human FNTB gene. This protein plays a role in protein farnesylation.
National Institutes of Health

Related topics

Related topics

7 relations
Enzyme GeneFNTB geneFNTB wt AlleleProtein Complex Subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The regulator of G protein signaling ( RGS ) domain of G protein-coupled receptor kinase 5 ( GRK 5 ) regulates plasma membrane localization and function
The G protein–coupled receptor (GPCR) kinases (GRKs) phosphorylate activated GPCRs at the plasma membrane (PM). Here GRK5/GRK4… 
2015
2015
The FNTB promoter polymorphism rs11623866 as a potential predictive biomarker for lonafarnib treatment of ovarian cancer patients.
AIM Despite promising preclinical findings regarding clinical utility of farnesyltransferase inhibitors (FTI), such as lonafarnib… 
Review
2014
Review
2014
Mo1399 Gastrointestinal Stromal Tumors: a Systematic Review of Diagnostic Yield and Complication Rates of Endoscopic Ultrasound Fine Needle Biopsy
2014
2014
The FNTB-609G>C polymorphism as a possible predictive factor for efficacy of lonafarnib-treatment? Exploratory analysis of a randomized phase II clinical trial in stage IIb-IV ovarian cancer, treated…
e16534 Background: Despite promising preclinical findings regarding clinical utility of farnesyltransferase inhibitors (FTI… 
2011
2011
FPTB, a Novel CA-4 Derivative, Induces Cell Apoptosis of Human Chondrosarcoma Cells Through Mitochondrial Dysfunction and Endoplasmic Reticulum Stress Pathways
2010
2010
Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study
Laminopathies are rare monogenic diseases, some of them exhibiting features of the metabolic syndrome. These diseases are mainly… 
2005
2005
Isolation of a cDNA encoding the alpha-subunit of CAAX-prenyltransferases from Catharanthus roseus and the expression of the active recombinant protein farnesyltransferase.
Crfta/ggt_Ia (AF525030), a cDNA encoding the ?-subunit of the two types of CaaX-prenyltransferase (CaaX-PTase), i.e. protein… 
Review
2002
Review
2002
[CAAX peptidomimetics: their farnesyltransferase inhibition activity and antitumor effect].
  • J. Ohkanda
  • Seikagaku. The Journal of Japanese Biochemical…
  • 2002
  • Corpus ID: 26975688
1997
1997
Synthesis and biological activity of semipeptoid farnesyltransferase inhibitors.
Review
1997
Review
1997
Advances in the development of farnesyltransferase inhibitors: Substrate recognition by protein farnesyltransferase
A variety of compounds that show promise in cancer chemotherapy and chemoprevention have been identified as farnesyltransferase… 
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