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FNTB gene

Known as: FPTB, FNTB, FARNESYLTRANSFERASE, CAAX BOX, BETA 
This gene is involved in subcellular protein targeting and the post-translational modification of certain proteins.
National Institutes of Health

Related topics

Related topics

3 relations
FNTB protein, humanintracellular protein transport

Narrower (1)

FNTB wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Deletion of the Major Facilitator Superfamily Transporter fptB Alters Host Cell Interactions and Attenuates Virulence of Type A Francisella tularensis
ABSTRACT Francisella tularensis is a Gram-negative, facultative, intracellular coccobacillus that can infect a wide variety of… 
2018
2018
Assessment of Protein Prenylation Pathway in Multiple Sclerosis Patients
Multiple sclerosis (MS) is a chronic inflammatory disorder with several genetic and environmental factors being implicated in its… 
2015
2015
The FNTB promoter polymorphism rs11623866 as a potential predictive biomarker for lonafarnib treatment of ovarian cancer patients.
AIM Despite promising preclinical findings regarding clinical utility of farnesyltransferase inhibitors (FTI), such as lonafarnib… 
2013
2013
Alteration of Mevalonate Pathway Related Enzyme Expressions in Pressure Overload-Induced Cardiac Hypertrophy and Associated Heart Failure with Preserved Ejection Fraction
Background: Abnormalities of the mevalonate pathway, an important cellular metabolic pathway, are common in many diseases… 
2013
2013
Gene expression analysis in response to osmotic stimuli in the intervertebral disc with DNA microarray
BackgroundIntervertebral disc (IVD) cells experience a broad range of physicochemical stimuli under physiologic conditions… 
Highly Cited
2011
Highly Cited
2011
High prevalence of laminopathies among patients with metabolic syndrome.
Constitutional laminopathies, such as the Dunnigan familial partial lipodystrophy, are severe diseases caused by mutations in A… 
2011
2011
Polymorphismen im Promotor des Gens FNTB und deren mögliche Bedeutung bei malignen Neoplasien
Ziel der vorliegenden Untersuchungen war die strukturelle und funktionelle Analyse der Promotorregion des Gens FNTB. Dieses… 
Highly Cited
2006
Highly Cited
2006
Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation
ABSTRACT Like other small G proteins of the Ras superfamily, Rap1 is activated by distinct guanine nucleotide exchange factors… 
2003
2003
Biochemical, Structural and Cellular Studies on IIGP1, a member of the p47 Family of GTPases
My thesis work focuses on the biochemical, structural and cellular characterisation of IIGP1, a member of the p47 family of… 
1993
1993
cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences.
The CAAX farnesyltransferase is a heterodimeric enzyme that attaches a farnesyl group to a single cysteine in several cellular… 
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