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FMNL2 gene

Known as: FORMIN-LIKE 2, formin like 2, FMNL2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
CircHIPK3 promotes colorectal cancer cells proliferation and metastasis via modulating of miR-1207-5p/FMNL2 signal.
2017
2017
Long non-coding RNA TUG1 promotes progression of oral squamous cell carcinoma through upregulating FMNL2 by sponging miR-219.
Oral squamous cell carcinoma (OSCC) is a prevalent oral disease with a high morbidity and mortality rate. Several long non-coding… 
Highly Cited
2016
Highly Cited
2016
Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer
Circular RNAs (circRNAs), a large class of RNAs, have recently shown huge capabilities as gene regulators in mammals. Some of… 
Highly Cited
2016
Highly Cited
2016
MicroRNA-206 functions as a tumor suppressor in colorectal cancer by targeting FMNL2
  • X. RenG. He L. Liang
  • Journal of Cancer Research and Clinical Oncology
  • 2016
  • Corpus ID: 2526297
AbstractBackground Colorectal cancer (CRC) is one of the most common cancers in the world. MicroRNAs play important roles in the… 
Highly Cited
2015
Highly Cited
2015
Formin and capping protein together embrace the actin filament in a ménage à trois
Proteins targeting actin filament barbed ends play a pivotal role in motile processes. While formins enhance filament assembly… 
2015
2015
MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer.
Highly Cited
2015
Highly Cited
2015
The structure of FMNL2–Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation
Formins are actin polymerization factors that elongate unbranched actin filaments at the barbed end. Rho family GTPases activate… 
Highly Cited
2013
Highly Cited
2013
MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.
BACKGROUND & AIMS Formin-like (FMNL)2 is up-regulated in colorectal tumors and has been associated with tumor progression, but… 
Highly Cited
2012
Highly Cited
2012
FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42
Highly Cited
2010
Highly Cited
2010
FMNL2 Enhances Invasion of Colorectal Carcinoma by Inducing Epithelial-Mesenchymal Transition
FMNL2 is a member of diaphanous-related formins that control actin-dependent processes such as cell motility and invasion. Its… 
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