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FMNL2 gene

Known as: FORMIN-LIKE 2, formin like 2, FMNL2 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer
Circular RNAs (circRNAs), a large class of RNAs, have recently shown huge capabilities as gene regulators in mammals. Some of… Expand
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Highly Cited
2015
Highly Cited
2015
Formin and capping protein together embrace the actin filament in a ménage à trois
Proteins targeting actin filament barbed ends play a pivotal role in motile processes. While formins enhance filament assembly… Expand
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2015
2015
MicroRNA-206 functions as a tumor suppressor in colorectal cancer by targeting FMNL2
  • X. Ren, G. He, +9 authors L. Liang
  • Journal of Cancer Research and Clinical Oncology
  • 2015
    • Corpus ID: 2526297
AbstractBackground Colorectal cancer (CRC) is one of the most common cancers in the world. MicroRNAs play important roles in the… Expand
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2015
2015
The structure of FMNL2–Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation
Formins are actin polymerization factors that elongate unbranched actin filaments at the barbed end. Rho family GTPases activate… Expand
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2015
2015
MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer.
Colorectal cancer (CRC) is one of the most common malignancies. Increasing evidences indicate that dysregulation of miRNAs is a… Expand
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Highly Cited
2013
Highly Cited
2013
MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.
BACKGROUND & AIMS Formin-like (FMNL)2 is up-regulated in colorectal tumors and has been associated with tumor progression, but… Expand
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Highly Cited
2012
Highly Cited
2012
FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42
Summary Cell migration entails protrusion of lamellipodia, densely packed networks of actin filaments at the cell front… Expand
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Highly Cited
2010
Highly Cited
2010
FMNL2 Enhances Invasion of Colorectal Carcinoma by Inducing Epithelial-Mesenchymal Transition
FMNL2 is a member of diaphanous-related formins that control actin-dependent processes such as cell motility and invasion. Its… Expand
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2009
2009
Characterization of Diaphanous-related formin FMNL2 in human tissues
BackgroundDiaphanous-related formins govern actin-based processes involved in many cellular functions, such as cell movement and… Expand
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2003
2003
Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.
FMNL (NM_005892.2) is a 5'-truncated partial cDNA encoding a Formin-homology protein related to DAAM1, DAAM2, DIAPH1 and DIAPH2… Expand
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