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FLOT1 protein, human

Known as: Integral Membrane Component Of Caveolae, flotillin-1 protein, human, Flotillin-1 
Flotillin-1 (427 aa, ~47 kDa) is encoded by the human FLOT1 gene. This protein may be involved in caveolae formation.
National Institutes of Health

Related topics

Related topics

4 relations
FLOT1 geneStructural gene

Broader (2)

flotillin-1flotillins

Papers overview

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Highly Cited
2016
Highly Cited
2016
DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression
Parkinson’s disease (PD) is a common chronic and progressive neurodegenerative disorder. Although the cause of PD is still poorly… 
Highly Cited
2012
Highly Cited
2012
Flotillin-1/Reggie-2 Protein Plays Dual Role in Activation of Receptor-tyrosine Kinase/Mitogen-activated Protein Kinase Signaling*
Background: We have analyzed the role of flotillins during EGF receptor signaling. Results: Flotillin-1 knockdown results in… 
Highly Cited
2011
Highly Cited
2011
Erratum: A lateralized brain network for visuospatial attention
Nat. Neurosci. 14, 1245–1246 (2011); published online 18 September 2011; corrected after print 13 October 2011 In the version of… 
Highly Cited
2006
Highly Cited
2006
Spatial and temporal regulation of GLUT4 translocation by flotillin‐1 and caveolin‐3 in skeletal muscle cells
Skeletal muscle tissue is one of the main sites where glucose uptake occurs in response to insulin. The glucose transporter type… 
Highly Cited
2005
Highly Cited
2005
The Stomatin/Prohibitin/Flotillin/HflK/C Domain of Flotillin-1 Contains Distinct Sequences That Direct Plasma Membrane Localization and Protein Interactions in 3T3-L1 Adipocytes*
Flotillin-1 is a lipid raft-associated protein that has been implicated in various cellular processes. We examined the… 
Highly Cited
2005
Highly Cited
2005
PTOV1 Enables the Nuclear Translocation and Mitogenic Activity of Flotillin-1, a Major Protein of Lipid Rafts
ABSTRACT PTOV1 is a mitogenic protein that shuttles between the nucleus and the cytoplasm in a cell cycle-dependent manner. It… 
Highly Cited
2004
Highly Cited
2004
Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites
Protein tyrosine kinase Pyk2 and multifunctional adaptor protein Cbl are implicated in the regulation of the cytoskeleton in… 
Highly Cited
2004
Highly Cited
2004
Human neuroglobin interacts with flotillin-1, a lipid raft microdomain-associated protein.
Highly Cited
2003
Highly Cited
2003
Ultrastructural localization of flotillin-1 to cholesterol-rich membrane microdomains, rafts, in rat brain tissue
Highly Cited
2002
Highly Cited
2002
Flotillin-1/Reggie-2 Traffics to Surface Raft Domains via a Novel Golgi-independent Pathway
Flotillins are lipid raft-associated proteins, which have been implicated in neuronal regeneration and insulin signaling. We now… 
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