Skip to search formSkip to main contentSkip to account menu

FK-506

Known as: FK 506, FK506 
National Institutes of Health

Related topics

Related topics

4 relations
Anhydrous Tacrolimus

Broader (3)

AntibioticsImmunosuppressive AgentsTacrolimus

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Reversal of multidrug resistance by an immunosuppressive agent FK-506
SummaryFK-506, a novel immunosuppressive agent, was examined for its reversing effect on multidrug-resistant tumor cells. FK-506… 
Review
1999
Review
1999
Rational management of posttransplant lymphoproliferative disorder in pediatric recipients.
Review
1997
Review
1997
Expression and function of calcineurin in the mammalian nephron: physiological roles, receptor signaling, and ion transport.
Review
1994
Review
1994
Histopathology of the immune system as a tool to assess immunotoxicity.
Highly Cited
1994
Highly Cited
1994
FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818.
L-685,818 differs only slightly in structure from the immunosuppressive drug FK-506, and both compounds bind with comparable… 
Highly Cited
1993
Highly Cited
1993
FK‐506 AND METHOTREXATE PREVENT GRAFT‐VERSUS-HOST DISEASE IN DOGS GIVEN 9.2 Gy TOTAL BODY IRRADIATION AND MARROW GRAFTS FROM UNRELATED DOG LEUKOCYTE ANTIGEN‐NONIDENTICAL DONORS
FK-506 was evaluated either alone or combined with methotrexate (MTX) for prevention of graft-versus-host disease (GVHD) in dogs… 
1992
1992
FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type
FK-506-binding proteins (FKBPs), which in T cells are supposed to mediate the immunosuppressive effects of the compounds FK-506… 
Highly Cited
1989
Highly Cited
1989
Inhibition of T-lymphocyte activation by the immunosuppressive drug FK-506.
Nanamolar concentrations of the immunosuppressive drug FK-506 inhibit the induction of T-lymphocyte proliferation by the lectins… 
Highly Cited
1987
Highly Cited
1987
Biopharmaceutical aspects of FK-506.
FK is a potent immunosuppressive agent. FK can be analyzed in biologic fluids by EIA. The oral absorption of FK is rapid but… 
Highly Cited
1987
Highly Cited
1987
Canine kidney transplantation with FK-506 alone or in combination with cyclosporine and steroids.
The immunosuppressive agent FK permitted increased kidney transplant survival in dogs over a wide dose range, but with weight… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)