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FECH gene

Known as: IRON CHELATASE, FECH, HEME SYNTHASE 
National Institutes of Health

Related topics

Related topics

3 relations
Erythropoietic ProtoporphyriaFERROCHELATASEferrochelatase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Chelation of iron and zinc by protoporphyrin catalyzed by mitochondrial preparations.
1 Sonication, freezing and thawing, treatment of mitochondria with Tween-Span surfactants and other procedures applied to… 
1989
1989
Studies on regulatory mechanisms of heme biosynthesis in hepatocytes from normal and experimental-diabetic rats. Role of insulin.
In the present work we demonstrate that insulin decreases the phenobarbital-induced activities of delta-aminolevulinic acid… 
1987
1987
Inhibition of ferrochelatase during differentiation of murine erythroleukaemia cells.
During dimethyl sulphoxide-induced differentiation of DS-19 murine erythroleukaemia (MEL) cells, the activity of the terminal… 
1987
1987
Isolation of human ferrochelatase.
To the Editor.— Ferrochelatase (protoheme ferrolyase, EC 4.99.1.1) catalyzes the insertion of ferrous iron into protoporphyrin IX… 
1985
1985
Spectroscopic examination of the active site of bovine ferrochelatase.
Spectrofluorometric techniques have been employed to examine the active site of the terminal enzyme of the heme biosynthetic… 
1983
1983
The in vitro inhibition of hepatic ferrochelatase by divalent lead and other soft metal ions.
A solubilized protein with ferrochelatase activity has been extracted from hepatic mitochondria of Sprague-Dawley rats. Under… 
1983
1983
Patterns of porphyrin accumulation in response to chemicals in chick embryo liver cells.
Four patterns of porphyrin accumulation were observed by high-pressure liquid chromatography when chemicals were added to chick… 
1982
1982
The use of N-methylprotoporphyrin dimethyl ester to inhibit ferrochelatase in Rhodopseudomonas sphaeroides and its effect in promoting biosynthesis of magnesium tetrapyrroles.
N-Methylprotoporphyrin dimethyl ester inhibits ferrochelatase in isolated membranes of Rhodopseudomonas sphaeroides at low… 
1982
1982
A radiochemical assay for heme synthase activity.
A radiochemical assay for heme synthase (ferrochelatase) activity is described in this report. The principle of the assay is to… 
Highly Cited
1967
Highly Cited
1967
Studies on ferrochelatase. The effects of thiols and other factors on the determination of activity.
1. Haems are unstable under aerobic conditions in the presence of thiols, which are used to activate the ferrochelatase enzyme… 
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