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FERROCHELATASE

Known as: Ferro-Lyase, Protoheme, heme synthase, Porphyrin Metal Chelatase 
A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME… 
National Institutes of Health

Related topics

Related topics

14 relations
Erythropoietic ProtoporphyriaFECH geneFerrochelatase:CCnc:Pt:Ser:QnIn Blood

Broader (1)

Lyase

Narrower (2)

MET8 protein, S cerevisiaeZinc Chelatase

Papers overview

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Highly Cited
2005
Highly Cited
2005
Purification and substrate specificity of bovine liver-ferrochelatase.
Bovine ferrochelatase from liver mitochondria was purified 1434-fold with a 31% yield to apparent homogeneity by a procedure… 
2003
2003
Substrate binding to NO-ferro-naphthalene 1,2-dioxygenase studied by high-resolution Q-band pulsed 2H-ENDOR spectroscopy.
The active site of naphthalene 1,2-dioxygenase (NDO) contains a Rieske Fe-S cluster and a mononuclear non-heme iron, which are… 
1983
1983
Slowly progressive aphasia without generalized dementia
Highly Cited
1980
Highly Cited
1980
Chronic low-level lead toxicity in the rat. III. An integrated assessment of long-term toxicity with special reference to the kidney.
1980
1980
Drug-induced conversion of liver haem into modified porphyrins. Evidence for two classes of products.
A porphyrin with inhibitory activity towards protohaem ferro-lyase (EC 4.99.1.1) was isolated from the liver of mice given either… 
Review
1978
Review
1978
Some biochemical and clinical aspects of lead intoxication.
Highly Cited
1969
Highly Cited
1969
The structural organization of haem synthesis in rat liver mitochondria.
1. Anaerobic conditions are normally necessary for incorporation of iron into haems and only ferrous iron is used. After addition… 
1968
1968
Characterization and measurement of heme synthetase in normal human bone marrow.
The heme synthetase step in human bone marrow has been characterized in a crude lysate as an enzymatic reaction in that it has a… 
1968
1968
Studies on ferrochelatase. The enzymic formation of haem in proplastids, chloroplasts and plant mitochondria.
1. Ferrochelatase was demonstrated in the chloroplasts and proplastids isolated from the primary leaves of beans (a dicotyledon… 
Highly Cited
1963
Highly Cited
1963
ON THE ANOMALOUS INTERACTIONS OF LIGANDS WITH RHODOSPIRILLUM HAEM PROTEIN.
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