FERROCHELATASE

Known as: Ferro-Lyase, Protoheme, heme synthase, Porphyrin Metal Chelatase 
A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME… (More)
National Institutes of Health

Related topics

Related topics

14 relations
Erythropoietic ProtoporphyriaFECH geneFerrochelatase:CCnc:Pt:Ser:QnIn Blood
(More)

Broader (1)

Lyase

Narrower (2)

MET8 protein, S cerevisiaeZinc Chelatase

Papers overview

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Highly Cited
2011
Highly Cited
2011
Heme Synthesis by Plastid Ferrochelatase I Regulates Nuclear Gene Expression in Plants
Chloroplast signals regulate hundreds of nuclear genes during development and in response to stress, but little is known of the… (More)
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Highly Cited
2009
Highly Cited
2009
UC-EBG on LTCC for 60-GHz Frequency Band Antenna Applications
The relatively high dielectric constant of the low-temperature cofired ceramic (LTCC) substrate materials can reduce the antenna… (More)
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Highly Cited
2008
Highly Cited
2008
60-GHz Patch Antennas and Arrays on LTCC With Embedded-Cavity Substrates
The design is presented of aperture-coupled microstrip line-fed patch antennas (ACMPAs) and 4times4 planar arrays on Ferro A6-S… (More)
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Highly Cited
2004
Highly Cited
2004
Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis.
Human ferrochelatase, a mitochondrial membrane-associated protein, catalyzes the terminal step of heme biosynthesis by insertion… (More)
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Highly Cited
2004
Highly Cited
2004
Yeast frataxin solution structure, iron binding, and ferrochelatase interaction.
The mitochondrial protein frataxin is essential for cellular regulation of iron homeostasis. Although the exact function of… (More)
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Highly Cited
2002
Highly Cited
2002
Interaction between the bacterial iron response regulator and ferrochelatase mediates genetic control of heme biosynthesis.
The heme biosynthetic pathway culminates with the insertion of iron into protoporphyrin catalyzed by ferrochelatase. The… (More)
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Review
2000
Review
2000
Chemoprotection against cancer by induction of phase 2 enzymes.
Induction of Phase 2 enzymes is an effective and sufficient strategy for achieving protection against the toxic and neoplastic… (More)
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Review
2000
Review
2000
Ferrochelatase at the millennium: structures, mechanisms and [2Fe-2S] clusters
Ferrochelatase (E.C. 4.99.1.1, protoheme ferrolyase) catalyzes the insertion of ferrous iron into protoporphyrin IX to form… (More)
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Highly Cited
1997
Highly Cited
1997
Myoglobin discriminates between O2, NO, and CO by electrostatic interactions with the bound ligand
 Most biological substrates have distinctive sizes, shapes, and charge distributions which can be recognized specifically by… (More)
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1984
1984
Differential interaction of porphyrins used in photoradiation therapy with ferrochelatase.
The mechanism of porphyrin accumulation by tumours is not yet established. If metabolism aids porphyrin elimination, tumours… (More)
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