FD 891

Known as: 9,19-Dioxabicyclo(16.1.0)nonadeca-4,6,12,14-tetraen-8-one, 10-(4,6-dihydroxy-8-methoxy-1,5,7-trimethylnonyl)-2,17-dihydroxy-3,5,7-trimethyl-, FD-891 
 
National Institutes of Health

Papers overview

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2016
2016
To isolate a key polyketide biosynthetic intermediate for the 16-membered macrolide FD-891 (1), we inactivated two biosynthetic… (More)
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2014
2014
A concise and unified strategy for the synthesis of C1-C18 macrolactone fragments of FD-891 and FD-892 as well as their analogues… (More)
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2012
2012
FD-891, a structurally unique 16-membered macrolide having anticancer activity, was synthesized according to a strategy employing… (More)
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2010
2010
FD-891 is a 16-membered cytotoxic antibiotic macrolide that is especially active against human leukemia such as HL-60 and Jurkat… (More)
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2009
2009
The 16-membered macrolide FD-891 exerts cytotoxicity toward several cancer cell lines. In this study, we showed that FD-891… (More)
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2006
2006
The enantioselective synthesis of FD-891 has been achieved with a longest linear sequence of 21 steps. The synthetic strategy… (More)
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2006
2006
[reaction: see text] A total synthesis of the naturally occurring, cytotoxic macrolide FD-891 is described. Three fragments were… (More)
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1994
1994
New 18-membered macrolides FD-891 and FD-892 were discovered from the fermentation broth of Streptomyces graminofaciens A-8890… (More)
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1994
1994
Structures of FD-891 and FD-892 were determined by extensive NMR spectral analysis as shown in Fig. 1. They belong to such 18… (More)
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