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FD 891

Known as: 9,19-Dioxabicyclo(16.1.0)nonadeca-4,6,12,14-tetraen-8-one, 10-(4,6-dihydroxy-8-methoxy-1,5,7-trimethylnonyl)-2,17-dihydroxy-3,5,7-trimethyl-, FD-891 
 
National Institutes of Health

Papers overview

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2014
2014
A concise and unified strategy for the synthesis of C1-C18 macrolactone fragments of FD-891 and FD-892 as well as their analogues… Expand
Review
2014
Review
2014
Streptomyces is a large genus consisting of soil‐dwelling, filamentous bacteria that are best known for their capability of… Expand
2012
2012
FD-891, a structurally unique 16-membered macrolide having anticancer activity, was synthesized according to a strategy employing… Expand
2010
2010
FD‐891 is a 16‐membered cytotoxic antibiotic macrolide that is especially active against human leukemia such as HL‐60 and Jurkat… Expand
2006
2006
The enantioselective synthesis of FD-891 has been achieved with a longest linear sequence of 21 steps. The synthetic strategy… Expand
2006
2006
[reaction: see text] A total synthesis of the naturally occurring, cytotoxic macrolide FD-891 is described. Three fragments were… Expand
2002
2002
The absolute stereochemistry of FD-891, a novel cytotoxic 18-membered macrolactone antibiotic, was determined by a synthetic… Expand
2000
2000
FD-891 belongs to a group of 18-membered macrolides, and is a structural analogue of a specific inhibitor of vacuolar type H… Expand
1994
1994
New 18-membered macrolides FD-891 and FD-892 were discovered from the fermentation broth of Streptomyces graminofaciens A-8890… Expand
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1994
1994
Structures of FD-891 and FD-892 were determined by extensive NMR spectral analysis as shown in Fig. 1. They belong to such 18… Expand
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