• Publications
  • Influence
Differential Type I IFN-Inducing Abilities of Wild-Type versus Vaccine Strains of Measles Virus1
TLDR
The stem-loop structure, rather than full genome replication or specific internal sequences of the MV genome, is required for an early phase of type I IFN induction by MV in host cells. Expand
Structural basis for chemical inhibition of human blood coagulation factor Xa.
TLDR
Two epidermal growth factor-like domains of factor Xa are well ordered in both crystal forms as well as the region between the two domains, which recently was found to be the binding site of the effector cell protease receptor-1, which provides a basis for designing next generation inhibitors offactor Xa. Expand
Development of a sensitive two-site immunoradiometric assay for parathyroid hormone-related peptide: evidence for elevated levels in plasma from patients with adult T-cell leukemia/lymphoma and
TLDR
It is suggested that PTHrP is a major humoral factor responsible for the hypercalcemia frequently associated with adult T-cell leukemia/lymphoma and also with B-cell lymphoma. Expand
FD‐891, a structural analogue of concanamycin A that does not affect vacuolar acidification or perforin activity, yet potently prevents cytotoxic T lymphocyte‐mediated cytotoxicity through the
TLDR
FACS analysis for cell surface receptors revealed that FD-891 significantly reduced the expression of the T-cell receptor (TCR)/CD3 complex, suggesting that the blockage of conjugate formation and subsequent target cell killing might be at least partly owing to FD- 891-induced down-regulation ofThe TCR/ CD3 complex. Expand
Characteristics of the hemostatic action of KFA-1411, an inhibitor of coagulation factor Xa (FXa), in humans and various animals.
TLDR
Results indicate that KFA-1411 may exhibit antithrombotic efficacy without an unwanted platelet-related action in the future treatment of various thrombosis diseases. Expand
Evaluation of a New Blood Coagulation Factor Xa Inhibitor, KFA-1411, as an Anticoagulant in a Cynomolgus Monkey Hemodialysis Model: Parameters Suitable for Monitoring Anticoagulant Activities
TLDR
Results indicate that this selective FXa inhibitor could be used as an anticoagulant for hemodialysis, and both activated partial thromboplastin time (APTT) and prothrombin time (PT) can be used to monitor the anticoAGulant activity in the extracorporeal circulation. Expand
Virus Wild-Type versus Vaccine Strains of Measles Differential Type I IFN-Inducing Abilities of
TLDR
This article cites 59 articles, 27 of which can be accessed free at:Subscriptions http://www.jimmunol.org/etoc/subscriptions.shtml/ Receive free email-alerts when new articles cite this article. Expand