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FBXW7 gene

Known as: SEL10, C. ELEGANS, HOMOLOG OF, FLJ11071, AGO 
This gene is involved in ubiquitin-dependent proteolysis and regulation of the G1-S cell cycle checkpoint.
National Institutes of Health

Related topics

Related topics

3 relations
FBXW7 protein, humanUbiquitination

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FBXW7 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Quick-multiplex-consensus (QMC)-PCR followed by high-resolution melting: a simple and robust method for mutation detection in formalin-fixed paraffin-embedded tissue
Background Mutation detection in tumours will become increasingly important in pathological diagnosis as ‘predictive’ mutations… 
2009
2009
Role of the RNA-binding protein Nrd1 and Pmk1 mitogen-activated protein kinase in the regulation of myosin mRNA stability in fission yeast.
Myosin II is an essential component of the actomyosin contractile ring and plays a crucial role in cytokinesis by generating the… 
2006
2006
CDC4 gene expression as potential biomarker for targeted therapy in prostate cancer
Targeted therapy of proteasome regulated gene expression has potential utility in cancer treatment since components of ubiquitin… 
2001
2001
Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10.
The SCF complex is a type of ubiquitin ligase that consists of the invariable components SKP1, CUL1, and RBX1 as well as a… 
Highly Cited
1998
Highly Cited
1998
An Essential Domain within Cdc34p Is Required for Binding to a Complex Containing Cdc4p and Cdc53p in Saccharomyces cerevisiae *
The CDC34 gene of the yeastSaccharomyces cerevisiae encodes a ubiquitin-conjugating protein that transfers ubiquitin onto… 
Highly Cited
1997
Highly Cited
1997
Reference sera for antinuclear antibodies. II. Further definition of antibody specificities in international antinuclear antibody reference sera by immunofluorescence and western blotting.
OBJECTIVE To define the fine specificity of the 10 reference sera used for determination of antinuclear antibodies (ANA) and ANA… 
1994
1994
Molecular characterization of the 77-kDa echinoderm microtubule-associated protein. Homology to the beta-transducin family.
1990
1990
The CDC4 gene product is associated with the yeast nuclear skeleton.
1984
1984
A relationship between the yeast cell cycle genes CDC4 and CDC36 and the ets sequence of oncogenic virus E26
We report here significant primary sequence homology among the predicted translational products of three genes: CDC4, CDC36 and… 
1977
1977
Effects of the mitotic cell-cycle mutation cdc4 on yeast meiosis.
The mitotic cell-cycle mutation cdc4 has been reported to block the initiation of nuclear DNA replication and the separation of… 
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