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FBXO5 wt Allele

Known as: EMI1, Xenopus, Homolog of Gene, FBX5, Fbxo31 
Human FBXO5 wild-type allele is located within 6q25-q26 and is approximately 13 kb in length. This allele, which encodes F-box only protein 5, is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Summary The transition from G1 into DNA replication (S phase) is an emergent behavior resulting from dynamic and complex… Expand
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Highly Cited
2013
Highly Cited
2013
The anaphase-promoting complex (APC) is the crucial ubiquitin ligase targeting the regulatory machinery of the cell cycle. Emi1… Expand
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2013
2013
Neuronal development requires proper migration, polarization and establishment of axons and dendrites. Growing evidence… Expand
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Highly Cited
2009
Highly Cited
2009
In response to DNA damage, eukaryotic cells initiate a complex signalling pathway, termed the DNA damage response (DDR), which… Expand
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2008
2008
Clear cell carcinoma is a clinically and pathologically distinct entity among surface epithelial ovarian neoplasms, recognized… Expand
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Highly Cited
2006
Highly Cited
2006
The periodic destruction of mitotic cyclins is triggered by the activation of the anaphase-promoting complex/cyclosome (APC/C) in… Expand
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Highly Cited
2005
Highly Cited
2005
A BAC located in the 16q24.3 breast cancer loss of heterozygosity region was previously shown to restore cellular senescence when… Expand
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Highly Cited
2002
Highly Cited
2002
Emi1 promotes mitotic entry in Xenopus laevis embryos by inhibiting the APCCdc20 ubiquitination complex to allow accumulation of… Expand
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Highly Cited
2001
Highly Cited
2001
We have discovered an early mitotic inhibitor, Emi1, which regulates mitosis by inhibiting the anaphase promoting complex… Expand
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Highly Cited
2001
Highly Cited
2001
The anaphase-promoting complex/cyclosome (APC) ubiquitin ligase is activated by Cdc20 and Cdh1 and inhibited by Mad2 and the… Expand
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