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FBN2 protein, human

Known as: Fibrillin 2, Fibrillin-2, fibrillin 2 (congenital contractural arachnodactyly) protein, human 
Fibrillin-2 (2912 aa, ~315 kDa) is encoded by the human FBN2 gene. This protein is involved in the structure of extracellular calcium-binding… 
National Institutes of Health

Related topics

Related topics

17 relations
Calcium BindingCalcium-Binding ProteinsCell AdhesionCell Movement

Broader (1)

fibrillin-2

Papers overview

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2013
2013
Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug
Malignant mesothelioma is a form of cancer that is highly resistant to conventional cancer therapy for which no major therapeutic… 
2012
2012
Comparative Analysis of the Basement Membrane Composition of the Human Limbus Epithelium and Amniotic Membrane Epithelium
Purpose: Human amniotic membrane has been widely used as substrate for ex vivo expansion and transplantation of limbal epithelial… 
Highly Cited
2010
Highly Cited
2010
Enhanced fibrillin-2 expression is a general feature of wound healing and sclerosis: potential alteration of cell attachment and storage of TGF-β
Wound healing and sclerosis are characterized by an increase of extracellular matrix proteins, which are characteristically… 
2004
2004
Identification of a Major Microfibril-associated Glycoprotein-1-binding Domain in Fibrillin-2*
Using yeast two-hybrid, ligand blotting, and solid phase binding assays, we have shown that microfibril-associated glycoprotein-1… 
Highly Cited
2003
Highly Cited
2003
Tendon cell array isolation reveals a previously unknown fibrillin-2-containing macromolecular assembly.
Highly Cited
2002
Highly Cited
2002
Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.
Highly Cited
2000
Highly Cited
2000
Interaction of Tropoelastin with the Amino-terminal Domains of Fibrillin-1 and Fibrillin-2 Suggests a Role for the Fibrillins in Elastic Fiber Assembly*
Alignment of tropoelastin molecules during the process of elastogenesis is thought to require fibrillin-containing microfibrils… 
Review
1998
Review
1998
Morphogenesis of the First Blood Vessels
ABSTRACT: The initial phase of vessel formation is the establishment of nascent endothelial tubes from mesodermal precursor cells… 
1998
1998
Two-hybrid analysis reveals multiple direct interactions for thrombospondin 1.
Highly Cited
1996
Highly Cited
1996
Familial occurrence of typical and severe lethal congenital contractural arachnodactyly caused by missplicing of exon 34 of fibrillin-2.
Genetic linkage studies have linked congenital contractural arachnodactyly (CCA), a usually mild heritable connective-tissue… 
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