Skip to search formSkip to main contentSkip to account menu

FAD 286

Known as: FAD-286, FAD286 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Fadrozole

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The Aldosterone Synthase Inhibitor FAD286 is Suitable for Lowering Aldosterone Levels in ZDF Rats but not in db/db Mice
Abstract Inhibition of aldosterone synthase is an alternative treatment option to mineralocorticoid receptor antagonism to… 
2012
2012
Letter by Keidar and Gamliel-Lazarovich regarding article, "Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo…
To the Editor: We read with great interest the recent report by Calhoun et al1 in which the authors tested the effect of a novel… 
2010
2010
FAD286, an aldosterone synthase inhibitor, reduced atherosclerosis and inflammation in apolipoprotein E-deficient mice
Introduction Aldosterone is known to be involved in atherosclerosis and cardiovascular disease and blockade of its receptor was… 
2010
2010
FAD286, an Aldosterone Synthase Inhibitor, Reduces Retinal Vasculopathy
2009
2009
Coexpression of CYP11B2 or CYP11B1 with adrenodoxin and adrenodoxin reductase for assessing the potency and selectivity of aldosterone synthase inhibitors.
2009
2009
Sodium chloride and aldosterone: harbingers of hypertension-related cardiovascular disease.
Both dietary NaCl consumption and aldosterone have been implicated in the pathogenesis of hypertension-related cardiovascular… 
2009
2009
Trilostane, FAD286, and the role of aldosterone in the central regulation of blood pressure: focus on "Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt…
in a previous issue of this journal, Elise Gomez-Sanchez et al. ([4][1]) presented unequivocal evidence that… 
2008
2008
Central infusion of aldosterone synthase inhibitor attenuates left ventricular dysfunction and remodelling in rats after myocardial infarction.
AIMS Blockade of mineralocorticoid receptors in the central nervous system (CNS) prevents sympathetic hyperactivity and improves… 
2008
2008
Aldosterone and the autocrine modulation of potassium currents and oxidative stress in the diabetic rat heart
Aldosterone plays a major role in cardiac pathology. This study was designed to investigate the role of cardiac aldosterone in… 
2008
2008
The aldosterone synthase inhibitor FAD286 reduces plasma aldosterone concentration (PAC) with a long duration of action in a rat model of subchronic hyperaldosteronism
FAD286 (FAD) is a prototypical aldosterone synthase (CYP11B2) inhibitor that represents an alternative therapy to… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)