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Eukaryotic Initiation Factor-4A

Known as: Eukaryotic Initiation Factor-4A [Chemical/Ingredient], Initiation Factor-4A, Eukaryotic, Peptide Initiation Factor EIF 4A 
A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of… (More)
National Institutes of Health

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2006-2018
01220062018

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13 relations
EIF4A1 geneIn BloodProcess of secretionadministration & dosage
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Eukaryotic Initiation Factor-4A1Eukaryotic Initiation Factor-4A3

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Eukaryotic Initiation Factor-4A
physiological aspects
agonists
chemical synthesis
standards characteristics
Process of secretion

Papers overview

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2018
2018
Characterisation of the biological response of Saccharomyces cerevisiae to the loss of an allele of the eukaryotic initiation factor 4A.
The translation initiation machinery is emerging as an important target for therapeutic intervention, with potential in the… (More)
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2018
2018
Rocaglates as dual-targeting agents for experimental cerebral malaria.
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated… (More)
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2016
2016
Concise Synthesis of a Pateamine A Analogue with In Vivo Anticancer Activity Based on an Iron-Catalyzed Pyrone Ring Opening/Cross-Coupling.
The marine macrolide pateamine A and its non-natural sibling DMDA-Pat A are potent translation inhibitors targeting the… (More)
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2016
2016
eIF4A RNA Helicase Associates with Cyclin-Dependent Protein Kinase A in Proliferating Cells and Is Modulated by Phosphorylation.
Eukaryotic initiation factor 4A (eIF4A) is a highly conserved RNA-stimulated ATPase and helicase involved in the initiation of… (More)
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2014
2014
Molecular characterization and phylogenetic analysis of the eukaryotic translation initiation factor 4A gene in Antheraea pernyi (Lepdoptera: Saturniidae).
Eukaryotic initiation factor 4A (eIF-4A) is an essential component for protein translation in eukaryotes. The eIF-4A gene (ApeIF… (More)
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Review
2011
Review
2011
A T-DNA mutation in the RNA helicase eIF4A confers a dose-dependent dwarfing phenotype in Brachypodium distachyon.
In a survey of the BrachyTAG mutant population of Brachypodium distachyon, we identified a line carrying a T-DNA insertion in one… (More)
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2008
2008
Proteomic analysis of miltefosine-resistant Leishmania reveals the possible involvement of eukaryotic initiation factor 4A (eIF4A).
Another explanation for recovery is that she was septic nd improved with antibiotic therapy, although the evience seems to be… (More)
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2007
2007
RNA visualization in live bacterial cells using fluorescent protein complementation
We describe a technique for the detection and localization of RNA transcripts in living cells. The method is based on fluorescent… (More)
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2006
2006
RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.
Eukaryotic initiation factor 4A (eIF4A) is a member of the DEAD-box family of putative RNA helicases whose members are involved… (More)
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