Eukaryotic Initiation Factor-3

Known as: Eukaryotic Peptide Initiation Factor 3, EIF-3, Peptide Initiation Factor EIF-3 
A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the… (More)
National Institutes of Health

Related topics

Related topics

16 relations
EIF3E geneEIF3E wt AlleleIn BloodProcess of secretion
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Narrower (4)

Eukaryotic Initiation Factor-3, Subunit 4Eukaryotic Initiation Factor-3, Subunit 8Eukaryotic Translation Initiation Factor 3, Subunit 6Prt1 protein, S cerevisiae

Papers overview

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2011
2011
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).
Protein fate in higher eukaryotes is controlled by three complexes that share conserved architectural elements: the proteasome… (More)
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Highly Cited
2008
Highly Cited
2008
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.
The eukaryotic initiation factor 3 (eIF3) plays an important role in translation initiation, acting as a docking site for several… (More)
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Highly Cited
2007
Highly Cited
2007
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.
Protein synthesis in mammalian cells requires initiation factor eIF3, an approximately 800-kDa protein complex that plays a… (More)
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2006
2006
On the functions of the h subunit of eukaryotic initiation factor 3 in late stages of translation initiation
The eukaryotic translation initiation factor 3 (eIF3) has multiple roles during the initiation of translation of cytoplasmic… (More)
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Highly Cited
2005
Highly Cited
2005
mTOR and S6K1 Mediate Assembly of the Translation Preinitiation Complex through Dynamic Protein Interchange and Ordered Phosphorylation Events
In response to nutrients, energy sufficiency, hormones, and mitogenic agents, S6K1 phosphorylates several targets linked to… (More)
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Highly Cited
2005
Highly Cited
2005
PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes
PCI/MPN domain protein complexes comprise the 19S proteasome lid, the COP9 signalosome (CSN), and eukaryotic translation… (More)
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Highly Cited
2000
Highly Cited
2000
A new pathway of translational regulation mediated by eukaryotic initiation factor 3.
We report a new pathway of translation regulation that may operate in interferon-treated or virus-infected mammalian cells. This… (More)
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2000
2000
Eukaryotic initiation factor 3 p110 mRNA is overexpressed in testicular seminomas.
Testicular germ cell tumors are important neoplasms and seminoma accounts for 40 to 50% of these tumors. Little is known… (More)
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Highly Cited
1998
Highly Cited
1998
Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAs.
Translation of hepatitis C virus (HCV) and classical swine fever virus (CSFV) RNAs is initiated by cap-independent attachment… (More)
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1978
1978
Localization of eukaryotic initiation factor 3 on native small ribosomal subunits.
The localization of eukaryotic initiation factor 3(eIF-3) on native small ribosomal subunits has been established by electron… (More)
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