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Eukaryotic Initiation Factor-2B, beta Subunit

Known as: EIF2B2, Eukaryotic Translation Initiation Factor 2B, Beta, Eukaryotic Translation Initiation Factor 2B Subunit 2 Beta 39-kDa 
Translation initiation factor eIF-2B subunit beta (351 aa, ~39 kDa) is encoded by the human EIF2B2 gene. This protein is involved in both GDP-GTP… 
National Institutes of Health

Related topics

Related topics

14 relations
EIF2B1 protein, humanEIF2B2 geneEIF2B4 geneEIF2B4 protein, human

Papers overview

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2019
2019
eIF2B:eIF2 complex
2012
2012
Identification of Intersubunit Domain Interactions within Eukaryotic Initiation Factor (eIF) 2B, the Nucleotide Exchange Factor for Translation Initiation*
Background: eIF2B is a critical translation factor and regulator of protein synthesis that is implicated in human disease… 
2010
2010
Components of the multifactor complex needed for internal initiation by the IRES of hepatitis C virus in Saccharomyces cerevisiae
Interaction between the 40S ribosomal subunit and the IRES of hepatitis C virus (HCV) is thought to be independent of initiation… 
Review
2009
Review
2009
[Eukaryotic translation initiation factor 2B and leukoencephalopathy with vanishing white matter].
Leukoencephalopathy with vanishing white matter (VWM) is one of the most prevalent inherited white matter disorders in childhood… 
Highly Cited
2007
Highly Cited
2007
A synthetic protein approach toward accurate mass spectrometric quantification of component stoichiometry of multiprotein complexes.
Quantitative description of protein interactions is crucial to understand and model molecular systems regulating various cellular… 
Highly Cited
2001
Highly Cited
2001
Possible mechanisms involved in the down-regulation of translation during transient global ischaemia in the rat brain.
The striking correlation between neuronal vulnerability and down-regulation of translation suggests that this cellular process… 
2000
2000
Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation.
1996
1996
eIF2B, the guanine nucleotide-exchange factor for eukaryotic initiation factor 2. Sequence conservation between the alpha, beta and delta subunits of eIF2B from mammals and yeast.
The guanine nucleotide-exchange factor eIF2B mediates the exchange of GDP bound to translation initiation factor eIF2 for GTP… 
1996
1996
eIF 2 B , the guanine nucleotide-exchange factor for eukaryotic initiation factor 2 Sequence conservation between the α , β and δ subunits of eIF 2 B from mammals and yeast
The guanine nucleotide-exchange factor eIF2B mediates the exchange of GDP bound to translation initiation factor eIF2 for GTP… 
Review
1994
Review
1994
Expression of initiation factor genes in mammalian cells.
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