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EIF2B4 gene

Known as: EIF2B4, EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, DELTA, EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, SUBUNIT 4 
This gene is involved in both the initiation and regulation of protein synthesis.
National Institutes of Health

Related topics

Related topics

14 relations
EIF2B1 geneEIF2B1 protein, humanEIF2B2 geneEIF2B3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A Novel Mutation in the EIF2B4 Gene Associated with Leukoencephalopathy with Vanishing White Matter
Leukoencephalopathy with vanishing white matter (VWM; MIM #603896) is an autosomal recessive disorder, characterized by childhood… 
2018
2018
Axonal abnormalities in vanishing white matter
We aimed to study the occurrence and development of axonal pathology and the influence of astrocytes in vanishing white matter. 
2018
2018
Epilepsy and ovarian failure: Two cases of adolescent-onset ovarioleukodystrophy
2015
2015
Adult‐onset vanishing white matter disease with novel missense mutations in a subunit of translational regulator, EIF2B4
To the Editor: Vanishing white matter disease (VWM) is one of the most prevalent inherited leucoencephalopathies with autosomal… 
2013
2013
P235 – 2075 Prenatal onset of vanishing white matter caused by a novel EIF2B4 mutation
2008
2008
Inhibition of a eukaryotic initiation factor (eIF2Bδ,/F11A3.2) during adulthood extends lifespan in Caenorhabditis elegans
The critical role of protein synthesis in regulating lifespan has been evidenced. This study shows that adult‐onset RNAi… 
Review
2008
Review
2008
Vanishing White Matter Disease: The First Reported Chinese Patient
Vanishing white matter disease is a rare neurological disease. The majority of patients reported are Caucasian individuals. We… 
Review
2006
Review
2006
The spectrum of mutations for the diagnosis of vanishing white matter disease
Vanishing white matter disease (VWM; MIM #603896), also known as childhood ataxia with central nervous system hypomyelination… 
Highly Cited
2004
Highly Cited
2004
Mutations Causing Childhood Ataxia with Central Nervous System Hypomyelination Reduce Eukaryotic Initiation Factor 2B Complex Formation and Activity
ABSTRACT Childhood ataxia with central nervous system hypomyelination (CACH), or vanishing white matter leukoencephalopathy (VWM… 
Review
2003
Review
2003
Leukoencephalopathy With Vanishing White Matter: From Magnetic Resonance Imaging Pattern to Five Genes
Leukoencephalopathy with vanishing white matter can be diagnosed on the basis of distinct clinical and magnetic resonance imaging… 
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