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EIF2B1 protein, human

Known as: Eukaryotic Translation Initiation Factor 2B, EIF2B-Alpha, Eukaryotic Translation Initiation Factor 2B, Alpha 
Translation initiation factor eIF-2B subunit alpha (305 aa, ~34 kDa) is encoded by the human EIF2B1 gene. This protein plays a role in both the… Expand
National Institutes of Health

Papers overview

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Review
2005
Review
2005
  • C. Proud
  • Seminars in cell & developmental biology
  • 2005
  • Corpus ID: 30700985
Eukaryotic initiation factor eIF2 and its 'exchange factor' eIF2B play a key role in the regulation of protein synthesis in… Expand
Highly Cited
2002
Highly Cited
2002
  • Marjo S. van der Knaap, Peter A. J. Leegwater, +5 authors Jan C. Pronk
  • Annals of neurology
  • 2002
  • Corpus ID: 1849575
Leukoencephalopathy with vanishing white matter is a recently defined autosomal recessive disorder. The course is chronic… Expand
Highly Cited
2002
Highly Cited
2002
This study examined potential mechanisms contributing to the inhibition of protein synthesis in skeletal muscle and heart after… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT The phosphatidylinositol 3-kinase (PI 3-kinase)/Akt signaling pathway is an important mediator of growth factor… Expand
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Highly Cited
2000
Highly Cited
2000
Phosphorylation of serine 51 residue on the alpha-subunit of eukaryotic initiation factor 2 (eIF2alpha) inhibits the guanine… Expand
Highly Cited
2000
Highly Cited
2000
Glucocorticoids are diabetogenic factors that not only antagonize the action of insulin in target tissues but also render these… Expand
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Highly Cited
1998
Highly Cited
1998
Eukaryotic initiation factor eIF2B catalyses a key regulatory step in mRNA translation. eIF2B and total protein synthesis are… Expand
Review
1997
Review
1997
Insulin acutely stimulates protein synthesis in mammalian cells, and this involves activation of the process of mRNA translation… Expand
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Review
1994
Review
1994
Eukaryotic initiation factor eIF-2B catalyses the exchange of guanine nucleotides on another translation initiation factor, eIF-2… Expand
Highly Cited
1985
Highly Cited
1985
The virus-associated VAI RNA of adenovirus is a small, RNA polymerase III-transcribed species required for efficient translation… Expand
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