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EIF2B1 protein, human

Known as: Eukaryotic Translation Initiation Factor 2B, EIF2B-Alpha, Eukaryotic Translation Initiation Factor 2B, Alpha 
Translation initiation factor eIF-2B subunit alpha (305 aa, ~34 kDa) is encoded by the human EIF2B1 gene. This protein plays a role in both the… Expand
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Eukaryotic initiation factor eIF2 and its 'exchange factor' eIF2B play a key role in the regulation of protein synthesis in… Expand
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Highly Cited
2002
Highly Cited
2002
This study examined potential mechanisms contributing to the inhibition of protein synthesis in skeletal muscle and heart after… Expand
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Highly Cited
2002
Highly Cited
2002
This study examined potential mechanisms contributing to the inhibition of protein synthesis in skeletal muscle and heart after… Expand
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Highly Cited
2002
Highly Cited
2002
The phosphatidylinositol 3-kinase (PI 3-kinase)/Akt signaling pathway is an important mediator of growth factor-dependent… Expand
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Highly Cited
2000
Highly Cited
2000
Glucocorticoids are diabetogenic factors that not only antagonize the action of insulin in target tissues but also render these… Expand
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Highly Cited
2000
Highly Cited
2000
Phosphorylation of serine 51 residue on the alpha-subunit of eukaryotic initiation factor 2 (eIF2alpha) inhibits the guanine… Expand
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Highly Cited
2000
Highly Cited
2000
PKR is a double-stranded (ds) RNA activated protein kinase whose expression is induced by interferon. Activated PKR… Expand
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Highly Cited
1998
Highly Cited
1998
Eukaryotic initiation factor eIF2B catalyses a key regulatory step in mRNA translation. eIF2B and total protein synthesis are… Expand
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Review
1997
Review
1997
Insulin acutely stimulates protein synthesis in mammalian cells, and this involves activation of the process of mRNA translation… Expand
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Highly Cited
1996
Highly Cited
1996
Eukaryotic translation initiation factor 2B (eIF2B) is a five-subunit complex that catalyzes guanine nucleotide exchange on eIF2… Expand
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