Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Ethylmorphine-N-Demethylase

Known as: Ethylmorphine N Demethylase, Demethylase, Ethylmorphine N, N Demethylase, Ethylmorphine 
A drug-metabolizing enzyme of the hepatic microsomal oxidase system which catalyzes the oxidation of the N-methyl group of ethylmorphine with the… Expand
National Institutes of Health

Related topics

Related topics

7 relations
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
In vivo cimetidine inhibits hepatic CYP2C6 and CYP2C11 but not CYP1A1 in adult male rats.
We previously reported that in vivo cimetidine inhibits hepatic microsomal enzyme activities mediated by cytochrome P450 (CYP… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1985
Highly Cited
1985
Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism.
Piperine, a major active component of black and long peppers, has been reported to enhance drug bioavailability. The present… Expand
Is this relevant?
1978
1978
Studies on the cellular toxicity of polychlorinated biphenyls (PCBs)
SummaryThe acute effects of the PCB (polychlorinated biphenyls) mixture (Aroclor 1254) on microsomal enzymes and on synthesis and… Expand
Is this relevant?
1978
1978
A quantitative analysis of fine structure and drug metabolism in livers of clofibrate-treated young adult and retired breeder rats.
The effects of clofibrate on the fine structure and drug-metabolizing capacity of livers of normolipidemic young adult virgin (YA… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
1978
1978
Effect of the Tfm locus on the hepatic ethylmorphine N-demethylase system in mice.
The present study further investigates certain androgen specific and nonspecific responses in mouse liver. The hepatic cytochrome… Expand
Is this relevant?
Highly Cited
1976
Highly Cited
1976
NADPH-cytochrome P450 reductase.
Abstract The rate of reduction of cytochrome P450 in hepatic microsomes in the presence of NADPH has been measured with a dual… Expand
Is this relevant?
Highly Cited
1972
Highly Cited
1972
Inhibition of hepatic oxidative xenobiotic metabolism by piperonyl butoxide.
Abstract The oxidative metabolism of piperonyl butoxide to a metabolite which forms a complex with reduced cytochrome P-450 is… Expand
Is this relevant?
Highly Cited
1971
Highly Cited
1971
The effect of cobalt chloride administration on the synthesis of hepatic microsomal cytochrome P-450.
Abstract Cobalt chloride administration to rats stimulates erythropoesis but inhibits the synthesis of hepatic microsomal P-450… Expand
Is this relevant?
Highly Cited
1969
Highly Cited
1969
Alterations in kinetic constants for hepatic microsomal aniline hydroxylase and ethylmorphine N-demethylase associated with pregnancy in rats.
Kinetic constants were determined for hepatic microsomal aniline hydroxylase and ethylmorphine N-demethylase in control female… Expand
Is this relevant?
Highly Cited
1969
Highly Cited
1969
Changes in certain kinetic properties of hepatic microsomal aniline hydroxylase and ethylmorphine demethylase associated with postnatal development and maturation in male rats.
1. Changes in certain kinetic properties (V(max.) and apparent K(m)) of hepatic microsomal mixed-function oxidases have been… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE