Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Ethylmorphine-N-Demethylase

Known as: Ethylmorphine N Demethylase, Demethylase, Ethylmorphine N, N Demethylase, Ethylmorphine 
A drug-metabolizing enzyme of the hepatic microsomal oxidase system which catalyzes the oxidation of the N-methyl group of ethylmorphine with the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
We previously reported that in vivo cimetidine inhibits hepatic microsomal enzyme activities mediated by cytochrome P450 (CYP… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
1985
Highly Cited
1985
Piperine, a major active component of black and long peppers, has been reported to enhance drug bioavailability. The present… Expand
1983
1983
Guinea pig adrenals possess a distinctive zona reticularis which increases in volume as the animal matures, coming to occupy over… Expand
1978
1978
SummaryThe acute effects of the PCB (polychlorinated biphenyls) mixture (Aroclor 1254) on microsomal enzymes and on synthesis and… Expand
1978
1978
The effects of clofibrate on the fine structure and drug-metabolizing capacity of livers of normolipidemic young adult virgin (YA… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Highly Cited
1976
Highly Cited
1976
Abstract The rate of reduction of cytochrome P450 in hepatic microsomes in the presence of NADPH has been measured with a dual… Expand
Highly Cited
1972
Highly Cited
1972
  • M. Franklin
  • Biochemical pharmacology
  • 1972
  • Corpus ID: 27021878
Abstract The oxidative metabolism of piperonyl butoxide to a metabolite which forms a complex with reduced cytochrome P-450 is… Expand
Highly Cited
1971
Highly Cited
1971
Abstract Cobalt chloride administration to rats stimulates erythropoesis but inhibits the synthesis of hepatic microsomal P-450… Expand
Highly Cited
1969
Highly Cited
1969
Kinetic constants were determined for hepatic microsomal aniline hydroxylase and ethylmorphine N-demethylase in control female… Expand
Highly Cited
1969
Highly Cited
1969
1. Changes in certain kinetic properties (V(max.) and apparent K(m)) of hepatic microsomal mixed-function oxidases have been… Expand