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Ethylmorphine-N-Demethylase

Known as: Ethylmorphine N Demethylase, Demethylase, Ethylmorphine N, N Demethylase, Ethylmorphine 
A drug-metabolizing enzyme of the hepatic microsomal oxidase system which catalyzes the oxidation of the N-methyl group of ethylmorphine with the… Expand
National Institutes of Health

Papers overview

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1998
1998
We previously reported that in vivo cimetidine inhibits hepatic microsomal enzyme activities mediated by cytochrome P450 (CYP… Expand
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Highly Cited
1985
Highly Cited
1985
Piperine, a major active component of black and long peppers, has been reported to enhance drug bioavailability. The present… Expand
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1978
1978
SummaryThe acute effects of the PCB (polychlorinated biphenyls) mixture (Aroclor 1254) on microsomal enzymes and on synthesis and… Expand
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1978
1978
The effects of clofibrate on the fine structure and drug-metabolizing capacity of livers of normolipidemic young adult virgin (YA… Expand
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1978
1978
The present study further investigates certain androgen specific and nonspecific responses in mouse liver. The hepatic cytochrome… Expand
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Highly Cited
1976
Highly Cited
1976
Abstract The rate of reduction of cytochrome P450 in hepatic microsomes in the presence of NADPH has been measured with a dual… Expand
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Highly Cited
1972
Highly Cited
1972
Abstract The oxidative metabolism of piperonyl butoxide to a metabolite which forms a complex with reduced cytochrome P-450 is… Expand
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Highly Cited
1971
Highly Cited
1971
Abstract Cobalt chloride administration to rats stimulates erythropoesis but inhibits the synthesis of hepatic microsomal P-450… Expand
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Highly Cited
1969
Highly Cited
1969
Kinetic constants were determined for hepatic microsomal aniline hydroxylase and ethylmorphine N-demethylase in control female… Expand
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Highly Cited
1969
Highly Cited
1969
1. Changes in certain kinetic properties (V(max.) and apparent K(m)) of hepatic microsomal mixed-function oxidases have been… Expand
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