Ethosuximide

Known as: alpha-Ethyl-alpha-methylsuccinimide, 3-Methyl-3-ethylsuccinimide, alpha-Methyl-alpha-ethylsuccinimide 
A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
PURPOSE Determine the optimal initial monotherapy for children with newly diagnosed childhood absence epilepsy (CAE) based on 12… (More)
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Review
2007
Review
2007
Ethosuximide, 2-ethyl-2-methylsuccinimide, has been used extensively for "petit mal" seizures and it is a valuable agent in… (More)
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Highly Cited
2004
Highly Cited
2004
This paper describes the development of glucose biosensors based on carbon nanotube (CNT) nanoelectrode ensembles (NEEs) for the… (More)
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Highly Cited
2004
Highly Cited
2004
Poly(L-lysine)/hyaluronan (PLL/HA) films were chemically cross-linked with a water soluble carbodiimide (EDC) in combination with… (More)
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Highly Cited
2001
Highly Cited
2001
T-type Ca(2+) currents have been proposed to be involved in the genesis of spike-and-wave discharges, a sign of absence seizures… (More)
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Highly Cited
1998
Highly Cited
1998
The action of ethosuximide (ETX) on Na+, K+, and Ca2+ currents and on tonic and burst-firing patterns was investigated in rat and… (More)
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Highly Cited
1989
Highly Cited
1989
The mechanism by which ethosuximide reduces thalamic low-threshold calcium current (LTCC) was analyzed using voltage-clamp… (More)
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1987
1987
The hypothesis that cellular protein carboxyl-methylation reactions recognize altered aspartyl residues as part of a protein… (More)
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Highly Cited
1986
Highly Cited
1986
Effects of the anticonvulsant drugs sodium valproate (NaVP) and ethosuximide (ES) on mouse central (spinal cord and cortical… (More)
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1983
1983
Five patients had absence seizures refractory to treatment with either ethosuximide or valproate sodium. To determine their… (More)
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