Erythromycin

Known as: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione, Erythromycine, Erythromycin [Chemical/Ingredient] 
A broad-spectrum, macrolide antibiotic with antibacterial activity. Erythromycin diffuses through the bacterial cell membrane and reversibly binds to… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a carbapenem… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly recognized in infections among persons in the… (More)
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Highly Cited
2004
Highly Cited
2004
Certain concurrent medications increase plasma erythromycin concentration, sometimes causing tachycardia, ventricular arrhythmias… (More)
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Highly Cited
2003
Highly Cited
2003
Oxacillin-resistant Staphylococcus aureus (ORSA) is a virulent pathogen responsible for both health care-associated and community… (More)
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Highly Cited
2002
Highly Cited
2002
The rate of macrolide resistance among Streptococcus pneumoniae is increasing, but some investigators have questioned its… (More)
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Highly Cited
1998
Highly Cited
1998
Erythromycin resistance among streptococci is commonly due to target site modification by an rRNA-methylating enzyme, which… (More)
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Highly Cited
1998
Highly Cited
1998
Diffuse panbronchiolitis (DPB) is a chronic inflammatory disease of the airways with a high rate of mortality despite treatment… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND In the early 1990s there was an increase in erythromycin resistance among group A streptococci in Finland. In response… (More)
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Highly Cited
1996
Highly Cited
1996
Erythromycin resistance determinants include Erm methylases, efflux pumps, and inactivating enzymes. To distinguish the different… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND The use of erythromycin in Finland nearly tripled from 1979 to 1989. In 1988, we observed an unusually high frequency… (More)
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