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6-O-methylerythromycin B

Known as: Erythromycin, 12-deoxy-6-O-methyl- 
 
National Institutes of Health

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2 relations

Broader (1)

Erythromycin
analogs & derivatives

Papers overview

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2010
2010
Synthesis of 2′-O-acetate-3-keto-10,11-anhydro-12-O-acylimidazole-6-O-methylerythromycin
The key intermediate of preparing telithromycin,2′-O-acetate-3-keto-10,11-anhydro-12-O-acylimidazole-6-O-methylerythromycin,was… Expand
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1999
1999
Synthesis and antibacterial activities of novel 12-O-methylerythromycin A derivatives.
The novel erythromycin A derivatives: 9(S)-9-dihydro-12-O-methylerythromycin A (6) and 12-O-methyerythromycin A (3), have been… Expand
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1993
1993
Chemical modification of erythromycins. XII. A facile synthesis of clarithromycin (6-O-methylerythromycin A) via 2'-silylethers of erythromycin A derivatives.
 
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1993
1993
Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin.
Although erythromycin A contains five hydroxyl groups, regioselective methylation at the C-6 hydroxyl group was achieved to the… Expand
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1990
1990
Chemical modification of erythromycins. II. Synthesis and antibacterial activity of O-alkyl derivatives of erythromycin A.
A series of O-alkyl erythromycin A derivatives have been synthesized and their antibacterial activities compared with those of… Expand
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1990
1990
Chemical modification of erythromycins. IV. Synthesis and biological properties of 6-O-methylerythromycin B.
6-O-Methylerythromycin B has been synthesized from erythromycin B via regioselective methylation of the 6-hydroxyl group in 71… Expand
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1990
1990
Chemical modification of erythromycins. III. In vitro and in vivo antibacterial activities of new semisynthetic 6-O-methylerythromycins A, TE-031 (clarithromycin) and TE-032.
The in vitro and in vivo antibacterial activities of 6-O-methylerythromycin A (TE-031, A-56268, or clarithromycin) and 6,11-di-O… Expand
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1988
1988
Microbial transformation of 6-O-methylerythromycin derivatives.
Mucor circinelloides f. griseo-cyanus IFO 4563 was found to convert 6-O-methylerythromycin A (TE-031, A-56268) to (14R)-14… Expand
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1988
1988
14-Hydroxy-6-O-methylerythromycins A, active metabolites of 6-O-methylerythromycin A in human.
(14R)-14-Hydroxy-6-O-methylerythromycin A and (14S)-epimer have been isolated as active metabolites from human urine after oral… Expand
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Highly Cited
1984
Highly Cited
1984
Chemical modification of erythromycins. I. Synthesis and antibacterial activity of 6-O-methylerythromycins A.
The in vitro and in vivo antibacterial activities of 6-O-methylerythromycin A (TE-031, A-56268, or clarithromycin) and 6, 11-di-O… Expand
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