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6-O-methylerythromycin B
Known as:
Erythromycin, 12-deoxy-6-O-methyl-
National Institutes of Health
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2 relations
Broader (1)
Erythromycin
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Synthesis of 2′-O-acetate-3-keto-10,11-anhydro-12-O-acylimidazole-6-O-methylerythromycin
Cao Zhiling
,
Yao Guo-wei
,
L. Wei-wei
,
Xu-Ning Wei
2010
Corpus ID: 101347779
The key intermediate of preparing telithromycin,2′-O-acetate-3-keto-10,11-anhydro-12-O-acylimidazole-6-O-methylerythromycin,was…
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1999
1999
Synthesis and antibacterial activities of novel 12-O-methylerythromycin A derivatives.
Y. Ku
,
D. Riley
,
T. Grieme
,
A. Nilius
Journal of antibiotics (Tokyo. )
1999
Corpus ID: 24743989
The novel erythromycin A derivatives: 9(S)-9-dihydro-12-O-methylerythromycin A (6) and 12-O-methyerythromycin A (3), have been…
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1993
1993
Chemical modification of erythromycins. XII. A facile synthesis of clarithromycin (6-O-methylerythromycin A) via 2'-silylethers of erythromycin A derivatives.
Y. Watanabe
,
T. Adachi
,
T. Asaka
,
M. Kashimura
,
T. Matsunaga
,
S. Morimoto
Journal of antibiotics (Tokyo. )
1993
Corpus ID: 29987135
As reported in our previous paperX), clarithromycin (1, 6-0-methylerythromycin A) was efficiently synthesized starting from 2'-O…
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1993
1993
Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin.
Y. Watanabe
,
S. Morimoto
,
T. Adachi
,
M. Kashimura
,
T. Asaka
Journal of antibiotics (Tokyo. )
1993
Corpus ID: 26862120
Although erythromycin A contains five hydroxyl groups, regioselective methylation at the C-6 hydroxyl group was achieved to the…
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Highly Cited
1990
Highly Cited
1990
Chemical modification of erythromycins. II. Synthesis and antibacterial activity of O-alkyl derivatives of erythromycin A.
S. Morimoto
,
Y. Misawa
,
T. Adachi
,
T. Nagate
,
Y. Watanabe
,
S. Omura
Journal of antibiotics (Tokyo. )
1990
Corpus ID: 41211241
A series of O-alkyl erythromycin A derivatives have been synthesized and their antibacterial activities compared with those of…
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1990
1990
Chemical modification of erythromycins. IV. Synthesis and biological properties of 6-O-methylerythromycin B.
S. Morimoto
,
T. Adachi
,
Y. Misawa
,
T. Nagate
,
Y. Watanabe
,
S. Omura
Journal of antibiotics (Tokyo. )
1990
Corpus ID: 771424
6-O-Methylerythromycin B has been synthesized from erythromycin B via regioselective methylation of the 6-hydroxyl group in 71…
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1990
1990
Chemical modification of erythromycins. III. In vitro and in vivo antibacterial activities of new semisynthetic 6-O-methylerythromycins A, TE-031 (clarithromycin) and TE-032.
S. Morimoto
,
T. Nagate
,
+6 authors
S. Omura
Journal of antibiotics (Tokyo. )
1990
Corpus ID: 4806501
The in vitro and in vivo antibacterial activities of 6-O-methylerythromycin A (TE-031, A-56268, or clarithromycin) and 6,11-di-O…
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1988
1988
Microbial transformation of 6-O-methylerythromycin derivatives.
J. Sasaki
,
K. Mizoue
,
S. Morimoto
,
T. Adachi
,
S. Omura
Journal of antibiotics (Tokyo. )
1988
Corpus ID: 43800292
Mucor circinelloides f. griseo-cyanus IFO 4563 was found to convert 6-O-methylerythromycin A (TE-031, A-56268) to (14R)-14…
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1988
1988
14-Hydroxy-6-O-methylerythromycins A, active metabolites of 6-O-methylerythromycin A in human.
T. Adachi
,
S. Morimoto
,
H. Kondoh
,
T. Nagate
,
Y. Watanabe
,
K. Sota
Journal of antibiotics (Tokyo. )
1988
Corpus ID: 11161391
(14R)-14-Hydroxy-6-O-methylerythromycin A and (14S)-epimer have been isolated as active metabolites from human urine after oral…
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Highly Cited
1984
Highly Cited
1984
Chemical modification of erythromycins. I. Synthesis and antibacterial activity of 6-O-methylerythromycins A.
S. Morimoto
,
Y. Takahashi
,
Y. Watanabe
,
S. Omura
Journal of antibiotics (Tokyo. )
1984
Corpus ID: 44658614
The in vitro and in vivo antibacterial activities of 6-O-methylerythromycin A (TE-031, A-56268, or clarithromycin) and 6, 11-di-O…
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