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Epsilon-chain hemoglobin

Known as: Epsilon-Globin, Hemoglobin Epsilon Chain, Hemoglobin Subunit Epsilon 
Hemoglobin subunit epsilon (147 aa, ~16 kDa) is encoded by the human HBE1 gene. This protein plays a role in the transport of oxygen to tissues of… 
National Institutes of Health

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Related topics

8 relations
Cellular MembraneErythrocytesHBE1 geneHemoglobin

Papers overview

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Highly Cited
1996
Highly Cited
1996
Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome…
To analyze the function of the 5' DNase I hypersensitive sites (HSs) of the locus control region (LCR) on beta-like globin gene… 
Highly Cited
1993
Highly Cited
1993
Evidence that the transcription factor USF is a component of the human beta-globin locus control region heteromeric protein complex.
Highly Cited
1992
Highly Cited
1992
Individual stage selector element mutations lead to reciprocal changes in beta- vs. epsilon-globin gene transcription: genetic confirmation of promoter competition during globin gene switching.
Biochemical and genetic analysis of the embryonic to adult beta-like globin gene switch in chickens has led to the hypothesis… 
Highly Cited
1990
Highly Cited
1990
Negative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element
The human epsilon-globin gene has a number of alternative transcription initiation sites which correspond with regions of DNase I… 
Highly Cited
1990
Highly Cited
1990
A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation.
The locus activating region (LAR), contained within 30 kb of chromatin flanking the human beta-globin gene cluster, has recently… 
Highly Cited
1989
Highly Cited
1989
Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.
We have studied the 5'-flanking sequences required for the transcriptional regulation of human epsilon-globin gene expression. A… 
1989
1989
Chromatin structure of erythroid-specific genes of immature and mature chicken erythrocytes.
The beta-globin and histone H5 genes are transcriptionally active in immature chicken erythrocytes and potentially active in… 
1988
1988
Bidirectional control of the chicken beta- and epsilon-globin genes by a shared enhancer.
An enhancer specific to erythroid cells was identified previously in the 3' flanking sequence of the chicken adult beta-globin… 
Highly Cited
1984
Highly Cited
1984
Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells.
We have mapped the DNase I-hypersensitive sites around the epsilon-globin and c-myc genes in two human leukemia cell lines K562… 
Highly Cited
1980
Highly Cited
1980
The 5' flanking region of human epsilon-globin gene.
The structural analysis of the 2.0 kb region upstream from the epsilon-globin gene has been carried out. A genomic DNA map around… 
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