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Epsilon-chain hemoglobin

Known as: Epsilon-Globin, Hemoglobin Epsilon Chain, Hemoglobin Subunit Epsilon 
Hemoglobin subunit epsilon (147 aa, ~16 kDa) is encoded by the human HBE1 gene. This protein plays a role in the transport of oxygen to tissues of… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The developmental switch from human fetal (gamma) to adult (beta) hemoglobin represents a clinically important example of… 
Review
1996
Review
1996
It is now well understood that chromatin structure is perturbed in the neighborhood of expressed genes. This is most obvious in… 
Highly Cited
1995
Highly Cited
1995
The human epsilon‐globin gene is transcribed in erythroid cells only during the embryonic stages of development. Expression of… 
Highly Cited
1990
Highly Cited
1990
Four DNase I hypersensitive sites characterize the human beta‐globin Dominant Control Region (DCR) providing position independent… 
Highly Cited
1990
Highly Cited
1990
A powerful enhancer has been mapped to an 18-bp DNA segment located 11 kb 5' to the human epsilon-globin gene within the dominant… 
Highly Cited
1990
Highly Cited
1990
The mechanisms by which expression of the beta-like globin genes are developmentally regulated are under intense investigation… 
Highly Cited
1990
Highly Cited
1990
The Dominant Control Region (DCR) of the human beta‐globin gene locus consists of four strong hypersensitive sites (HSS) upstream… 
Highly Cited
1989
Highly Cited
1989
We have identified an erythroid-specific enhancer element far upstream of the human "beta-like globin" genes, at 10.2-11.0… 
Highly Cited
1986
Highly Cited
1986
The DNase I-hypersensitive sites in the human embryonic beta-globin gene region have been mapped in erythroid-enriched fractions… 
Highly Cited
1982
Highly Cited
1982
5-Azacytidine is a cytidine analogue that is capable of activating repressed genes in tissue-culture cells and has been shown to…