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Epoetin Alfa

Known as: Erythropoietin, 1-165-Erythropoietin (human clone lambdaHEPOFL13 protein moiety), glycoform alpha, EPO 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Abstract Protein glycosylation is post-translational modification (PTM) which is important for pharmacokinetics and… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Anemia, which is common in the critically ill, is often treated with red-cell transfusions, which are associated with… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Anemia, a common complication of chronic kidney disease, usually develops as a consequence of erythropoietin… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Anaemia is associated with poor cancer control, particularly in patients undergoing radiotherapy. We investigated… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE This randomized, double-blind, placebo-controlled clinical trial assessed the effects of epoetin alfa on transfusion… Expand
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Highly Cited
2000
Highly Cited
2000
Erythropoietin (EPO), recognized for its central role in erythropoiesis, also mediates neuroprotection when the recombinant form… Expand
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Highly Cited
1999
Highly Cited
1999
Novel erythropoiesis stimulating protein (NESP) is a hyperglycosylated analogue of recombinant human erythropoietin (Epoetin… Expand
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Highly Cited
1995
Highly Cited
1995
Hypoxia-inducible factor 1 (HIF-1) is a DNA-binding protein that activates erythropoietin (Epo) gene transcription in Hep3B cells… Expand
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Highly Cited
1993
Highly Cited
1993
Transcription of the human erythropoietin (EPO) gene is activated in Hep3B cells exposed to hypoxia. Hypoxia-inducible factor 1… Expand
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