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Epoetin Alfa

Known as: Erythropoietin, 1-165-Erythropoietin (human clone lambdaHEPOFL13 protein moiety), glycoform alpha, EPO 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Highly Cited
2007
BACKGROUND Anemia, which is common in the critically ill, is often treated with red-cell transfusions, which are associated with… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Anemia, a common complication of chronic kidney disease, usually develops as a consequence of erythropoietin… Expand
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Review
2005
Review
2005
PURPOSE To evaluate the effect on survival and quality of life of maintaining hemoglobin (Hb) in the range of 12 to 14 g/dL with… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Anaemia is associated with poor cancer control, particularly in patients undergoing radiotherapy. We investigated… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE This randomized, double-blind, placebo-controlled clinical trial assessed the effects of epoetin alfa on transfusion… Expand
Highly Cited
2000
Highly Cited
2000
Erythropoietin (EPO), recognized for its central role in erythropoiesis, also mediates neuroprotection when the recombinant form… Expand
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Highly Cited
1998
Highly Cited
1998
PURPOSE To evaluate prospectively the effectiveness of epoetin alfa as an adjunct to chemotherapy in patients with cancer based… Expand
Highly Cited
1995
Highly Cited
1995
  • Guang L. Wang, Gregg L. Semenza
  • The Journal of Biological Chemistry
  • 1995
  • Corpus ID: 41659164
Hypoxia-inducible factor 1 (HIF-1) is a DNA-binding protein that activates erythropoietin (Epo) gene transcription in Hep3B cells… Expand
Highly Cited
1993
Highly Cited
1993
  • G. Wang, G. Semenza
  • Proceedings of the National Academy of Sciences…
  • 1993
  • Corpus ID: 28961662
Transcription of the human erythropoietin (EPO) gene is activated in Hep3B cells exposed to hypoxia. Hypoxia-inducible factor 1… Expand