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Epoetin Alfa

Known as: Erythropoietin, 1-165-Erythropoietin (human clone lambdaHEPOFL13 protein moiety), glycoform alpha, EPO 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human erythropoietin (EPO). Produced primarily… Expand
National Institutes of Health

Related topics

Related topics

33 relations
1 ML Epoetin Alfa 3000 UNT/ML Injection [Procrit]1 ML Epoetin Alfa 4000 UNT/ML Injection [Procrit]AnemiaB-Cell Activation
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Narrower (7)

BinocritEpoetin Alfa HexalEpogenEprex
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Broader (2)

HematinicsRecombinant Erythropoietin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Impact of host cell line choice on glycan profile
Abstract Protein glycosylation is post-translational modification (PTM) which is important for pharmacokinetics and… Expand
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Highly Cited
2007
Highly Cited
2007
Efficacy and safety of epoetin alfa in critically ill patients.
BACKGROUND Anemia, which is common in the critically ill, is often treated with red-cell transfusions, which are associated with… Expand
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Highly Cited
2007
Highly Cited
2007
Correction of Anemia with Epoetin Alfa in Chronic Kidney DiseaseSingh AK, for the CHOIR Investigators (Harvard Med School; et al) N Engl J Med 355:2085–2098, 2006§
 
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Highly Cited
2006
Highly Cited
2006
Correction of anemia with epoetin alfa in chronic kidney disease.
BACKGROUND Anemia, a common complication of chronic kidney disease, usually develops as a consequence of erythropoietin… Expand
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Highly Cited
2003
Highly Cited
2003
Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial
BACKGROUND Anaemia is associated with poor cancer control, particularly in patients undergoing radiotherapy. We investigated… Expand
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Highly Cited
2001
Highly Cited
2001
Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial.
PURPOSE This randomized, double-blind, placebo-controlled clinical trial assessed the effects of epoetin alfa on transfusion… Expand
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Highly Cited
2000
Highly Cited
2000
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury.
Erythropoietin (EPO), recognized for its central role in erythropoiesis, also mediates neuroprotection when the recombinant form… Expand
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Highly Cited
1999
Highly Cited
1999
Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients.
Novel erythropoiesis stimulating protein (NESP) is a hyperglycosylated analogue of recombinant human erythropoietin (Epoetin… Expand
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Highly Cited
1995
Highly Cited
1995
Purification and Characterization of Hypoxia-inducible Factor 1 (*)
Hypoxia-inducible factor 1 (HIF-1) is a DNA-binding protein that activates erythropoietin (Epo) gene transcription in Hep3B cells… Expand
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Highly Cited
1993
Highly Cited
1993
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
Transcription of the human erythropoietin (EPO) gene is activated in Hep3B cells exposed to hypoxia. Hypoxia-inducible factor 1… Expand
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