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Entospletinib

Known as: 6-(1H-Indazol-6-yl)-N-(4-(morpholin-4-yl)phenyl)imidazo(1,2-a)pyrazin-8-amine, ENTO, Imidazo(1,2-a)pyrazin-8-amine, 6-(1H-indazol-6-yl)-N-(4-(4-morpholinyl)phenyl)- 
An orally available inhibitor of spleen tyrosine kinase (Syk), with potential antineoplastic activity. Upon oral administration of entospletinib… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

GS-9973
NCIt Antineoplastic Agent TerminologyReceptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Novel Targeted Therapies for Chronic Lymphocytic Leukemia in Elderly Patients: A Systematic Review.
2015
2015
The Combination of Entospletinib and Vincristine Demonstrates Synergistic Activity in a Broad Panel of Hematological Cancer Cell Lines and Anti-Tumor Efficacy in a DLBCL Xenograft Model
Background Entospletinib (GS-9973) selectively inhibits spleen tyrosine kinase (SYK), a critical signaling component of the BCR… 
2011
2011
Planthoppers of Delaware (Hemiptera, Fulgoroidea), excluding Delphacidae, with species Incidence from adjacent States
Abstract The number of species of planthoppers (excluding Delphacidae) known from Delaware is updated from 7 (in 4 families) to… 
2009
2009
Service-Learning in Entomology: Teaching, Research, and Outreach Domestically and Abroad
Insects are ideal models for demonstrating an array of biological and ecological concepts and the application of biology to solve… 
2004
2004
An electrophysiological characterization of projections from the pedunculopontine area to entopeduncular nucleus and globus pallidus in the cat
SummaryStimulation of the pedunculopontine region (PPN), in which neurons are filled by horseradish peroxidase injected into the… 
1995
1995
Alterations in pallidal neuronal responses to peripheral sensory and striatal stimulation in symptomatic and recovered Parkinsonian cats
Highly Cited
1994
Highly Cited
1994
The effects of lesions of the entorhinal cortex and the horizontal nucleus of the diagonal band of broca upon performance of a spatial location recognition task
1985
1985
Development of somatosensory responsiveness in the basal ganglia in awake cats.
Single-unit activity was recorded from the caudate nucleus (CD), globus pallidus, and entopeduncular nucleus (GP-ENTO) in awake… 
1979
1979
Development of responses of globus pallidus and entopeduncular nucleus neurons to stimulation of the caudate nucleus and precruciate cortex
1969
1969
Estudos laboratoriais de infecções humanas e de bovinos com vírus do grupo Pox
The authors describe the isolation and Identification of vaccinia virus fram a cow in farm where human vaccination had been… 
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