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Endothelin receptor antagonist
Known as:
antagonist endothelin receptor
, Antagonists, Endothelin
, Endothelin Receptor Antagonists
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A family of drugs that block the hormone endothelin and may prevent prostate cancer from spreading to the bones. They may also prevent the growth and…
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National Institutes of Health
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Related topics
Related topics
39 relations
Narrower (35)
A 216546
ATZ1993
BMS 184696
BMS 184697
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In Blood
aspects of radiation effects
chemical synthesis
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock
V. Krejčí
,
L. Hiltebrand
,
D. Erni
,
G. Sigurdsson
Critical Care Medicine
2003
Corpus ID: 9303586
ObjectiveSplanchnic ischemia is believed to play an important role in the development of multiple organ dysfunction in septic…
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Highly Cited
2001
Highly Cited
2001
Role of Endothelin B Receptors in Enhancing Endothelium-Dependent Nitric Oxide–Mediated Vascular Relaxation During High Salt Diet
J. B. Giardina
,
Gachavis M Green
,
A. Rinewalt
,
J. Granger
,
R. Khalil
HYPERTENSION
2001
Corpus ID: 20677093
High salt diet is often associated with increases in blood pressure, and the state of activation of endothelium-dependent…
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Highly Cited
1999
Highly Cited
1999
Functional proteomics of signal transduction by membrane receptors
Jasminka Godovac‐ Zimmermann
,
V. Soskic
,
S. Poznanović
,
Federico Brianza
Electrophoresis
1999
Corpus ID: 21074328
Functional proteomic methods have been developed and applied to the investigation of signal transduction systems involving…
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Review
1995
Review
1995
Therapeutic effects of endothelin receptor antagonists in stroke.
Frank C. Barone
,
R. Willette
,
Tian-Li Yue
,
G. Feurestein
Neurological Research
1995
Corpus ID: 32515694
The presence of the endothelin isopeptides and endothelin receptors on neurons, glial cells and brain capillary endothelium…
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Highly Cited
1994
Highly Cited
1994
Cyclic hexapeptide endothelin receptor antagonists highly potent for both receptor subtypes ETA and ETB.
T. Kikuchi
,
T. Ohtaki
,
+7 authors
T. Watanabe
Biochemical and Biophysical Research…
1994
Corpus ID: 13261492
A cyclic hexapeptide, cyclo(-D-Asp-Trp-Asp-D-Leu-Leu-D-Trp-), designed from cyclo(-D-Glu-Ala-D-alloisoleucyl-Leu-D-Trp-), an ETA…
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Highly Cited
1993
Highly Cited
1993
In vitro and in vivo studies with a series of hexapeptide endothelin antagonists.
A. Doherty
,
W. L. Cody
,
+7 authors
L. Davis
Journal of Cardiovascular Pharmacology
1993
Corpus ID: 33254300
The effects of different amino acids incorporated into the 16 and 17 positions of the C-terminal hexapeptide of ET-1 were…
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Highly Cited
1991
Highly Cited
1991
Platelets stimulate expression of endothelin mRNA and endothelin biosynthesis in cultured endothelial cells.
E. Ohlstein
,
B. Storer
,
J A Butcher
,
C. Debouck
,
G. Feuerstein
Circulation Research
1991
Corpus ID: 6865192
Modulation of the biosynthesis of the vasoconstrictor peptide endothelin was studied in cultured endothelial cells…
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Highly Cited
1991
Highly Cited
1991
Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy.
A. Benigni
,
F. Gaspari
,
+4 authors
G. Remuzzi
American Journal of Obstetrics and Gynecology
1991
Corpus ID: 31880254
Highly Cited
1990
Highly Cited
1990
Endothelin: a potent stimulus of atrial natriuretic peptide secretion by superfused rat atria and its dependency on calcium.
R. Schiebinger
,
C. Gomez-Sanchez
Endocrinology
1990
Corpus ID: 13010164
Endothelin, a hormone secreted by endothelial cells, has potent vasoconstrictive properties. Due to its potential paracrine…
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Highly Cited
1989
Highly Cited
1989
Lethal ischemia due to intracoronary endothelin in pigs.
D. Ezra
,
R. Goldstein
,
J. Czaja
,
G. Feuerstein
American Journal of Physiology
1989
Corpus ID: 29626469
Endothelin is a recently discovered endothelium-derived peptide with potent coronary constrictor properties in vitro. To evaluate…
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