Skip to search formSkip to main contentSkip to account menu

Endothelin receptor antagonist

Known as: antagonist endothelin receptor, Antagonists, Endothelin, Endothelin Receptor Antagonists 
A family of drugs that block the hormone endothelin and may prevent prostate cancer from spreading to the bones. They may also prevent the growth and… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (35)

A 216546ATZ1993BMS 184696BMS 184697
In Bloodaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock
ObjectiveSplanchnic ischemia is believed to play an important role in the development of multiple organ dysfunction in septic… 
Highly Cited
2001
Highly Cited
2001
Role of Endothelin B Receptors in Enhancing Endothelium-Dependent Nitric Oxide–Mediated Vascular Relaxation During High Salt Diet
High salt diet is often associated with increases in blood pressure, and the state of activation of endothelium-dependent… 
Highly Cited
1999
Highly Cited
1999
Functional proteomics of signal transduction by membrane receptors
Functional proteomic methods have been developed and applied to the investigation of signal transduction systems involving… 
Review
1995
Review
1995
Therapeutic effects of endothelin receptor antagonists in stroke.
The presence of the endothelin isopeptides and endothelin receptors on neurons, glial cells and brain capillary endothelium… 
Highly Cited
1994
Highly Cited
1994
Cyclic hexapeptide endothelin receptor antagonists highly potent for both receptor subtypes ETA and ETB.
A cyclic hexapeptide, cyclo(-D-Asp-Trp-Asp-D-Leu-Leu-D-Trp-), designed from cyclo(-D-Glu-Ala-D-alloisoleucyl-Leu-D-Trp-), an ETA… 
Highly Cited
1993
Highly Cited
1993
In vitro and in vivo studies with a series of hexapeptide endothelin antagonists.
The effects of different amino acids incorporated into the 16 and 17 positions of the C-terminal hexapeptide of ET-1 were… 
Highly Cited
1991
Highly Cited
1991
Platelets stimulate expression of endothelin mRNA and endothelin biosynthesis in cultured endothelial cells.
Modulation of the biosynthesis of the vasoconstrictor peptide endothelin was studied in cultured endothelial cells… 
Highly Cited
1991
Highly Cited
1991
Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy.
Highly Cited
1990
Highly Cited
1990
Endothelin: a potent stimulus of atrial natriuretic peptide secretion by superfused rat atria and its dependency on calcium.
Endothelin, a hormone secreted by endothelial cells, has potent vasoconstrictive properties. Due to its potential paracrine… 
Highly Cited
1989
Highly Cited
1989
Lethal ischemia due to intracoronary endothelin in pigs.
Endothelin is a recently discovered endothelium-derived peptide with potent coronary constrictor properties in vitro. To evaluate… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)