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Eflornithine Hydrochloride

Known as: Eflornithine.HCl, Hydrochloride, Eflornithine, Eflornithine Monohydrochloride, Monohydrate 
The hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits… Expand
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
BACKGROUND Few therapeutic options are available to treat the late-stage of human African trypanosomiasis, a neglected tropical… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Existing diagnostic and treatment tools for human African trypanosomiasis (HAT) are limited. The recent development of… Expand
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Highly Cited
2011
Highly Cited
2011
Graphical abstract Genome-scale RNA interference (RNAi) library screens in bloodstream-form Trypanosoma brucei, using nifurtimox… Expand
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Review
2011
Review
2011
Human African trypanosomiasis or 'sleeping sickness' is a neglected tropical disease caused by the parasite Trypanosoma brucei. A… Expand
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Highly Cited
2010
Highly Cited
2010
The success of nifurtimox-eflornithine combination therapy (NECT) for the treatment of human African trypanosomiasis (HAT) has… Expand
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Review
2010
Review
2010
Fatal if untreated, human African trypanosomiasis (HAT; sleeping sickness) afflicts an estimated 50,000–70,000 people each year… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Human African trypanosomiasis (HAT; sleeping sickness) caused by Trypanosoma brucei gambiense is a fatal disease… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for… Expand
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Highly Cited
2006
Highly Cited
2006
Objectives: Our objective was to compare the efficacy and safety of three drug combinations for the treatment of late-stage human… Expand
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