Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Eflornithine Hydrochloride

Known as: Eflornithine.HCl, Hydrochloride, Eflornithine, Eflornithine Monohydrochloride, Monohydrate 
The hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
BACKGROUND Few therapeutic options are available to treat the late-stage of human African trypanosomiasis, a neglected tropical… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Highly Cited
2013
Highly Cited
2013
BACKGROUND Existing diagnostic and treatment tools for human African trypanosomiasis (HAT) are limited. The recent development of… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
Review
2013
Review
2013
Abstract Despite the recent advances in drug research, finding a safe, effective, and easy to use chemotherapy for human African… Expand
Highly Cited
2011
Highly Cited
2011
Graphical abstract Genome-scale RNA interference (RNAi) library screens in bloodstream-form Trypanosoma brucei, using nifurtimox… Expand
  • figure 1
  • figure 2
Review
2011
Review
2011
Human African trypanosomiasis or 'sleeping sickness' is a neglected tropical disease caused by the parasite Trypanosoma brucei. A… Expand
Highly Cited
2010
Highly Cited
2010
ABSTRACT The success of nifurtimox-eflornithine combination therapy (NECT) for the treatment of human African trypanosomiasis… Expand
  • figure 1
  • figure 4
  • figure 2
  • figure 3
  • figure 5
Review
2010
Review
2010
  • C. Burri
  • Parasitology
  • 2010
  • Corpus ID: 38573878
SUMMARY For over fifty years, human African trypanosomiasis (HAT, sleeping sickness) has been treated with suramin, pentamidine… Expand
Review
2010
Review
2010
Fatal if untreated, human African trypanosomiasis (HAT; sleeping sickness) afflicts an estimated 50,000–70,000 people each year… Expand
  • figure 1
Highly Cited
2009
Highly Cited
2009
BACKGROUND Human African trypanosomiasis (HAT; sleeping sickness) caused by Trypanosoma brucei gambiense is a fatal disease… Expand
Highly Cited
2007
Highly Cited
2007
BACKGROUND Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for… Expand
  • figure 1
  • table 1
  • table 2