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Eflornithine Hydrochloride
Known as:
Eflornithine.HCl
, Hydrochloride, Eflornithine
, Eflornithine Monohydrochloride, Monohydrate
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The hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits…
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National Institutes of Health
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Related topics
Related topics
11 relations
African Trypanosomiasis
Antiprotozoal Agents
Decarboxylase Inhibitors [MoA]
Decreased Protein Synthesis [PE]
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Broader (1)
Eflornithine
Narrower (1)
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Synthesis of Eflornithine Hydrochloride and Related Substances by Novel Process
S. R. Patil
,
D. Pansare
,
Ashish Arsondkar
,
A. Bobade
,
Devan
,
B. Shinde
2018
Corpus ID: 102949443
The synthesis of five related substances/impurities of Eflornithine (5), formed during the preparation of Eflornithine bulk drug…
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2015
2015
Spectrophotometric determination of Eflornithine hydrochloride through schiff's base system using pdab reagent in pharmaceutical preparation
Amit Kumar
,
Vijender Singh
,
Praveen P Kumar
2015
Corpus ID: 62884899
A rapid, economic and highly sensitive spectrophotometric method was developed for the quantification of eflornithine…
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2013
2013
Characterisation and semi-mechanistic modelling of eflornithine pharmacokinetics and evalutation of prodrugs in oral treatment against late-stage human African trypanosomiasis
Carl C Johansson
2013
Corpus ID: 39973479
The present thesis explores the hypothesis that treatment of human African trypanosomiasis can be improved by characterising the…
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2009
2009
Estimation of eflornithine hydrochloride by UV spectroscopy
Amit Kumar
,
S. Prasad
,
S. Mohan
,
A.K. Singh
2009
Corpus ID: 103143616
A simple highly sensitive spectrophotometric method was developed for the quantification of Eflornithine hydrochloride (2…
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2009
2009
Multicenter clinical trial of nifurtimox-eflornithine therapy for second-stage sleeping sickness
G. Priotto
,
S. Kasparian
,
+13 authors
U. Karunakara
2009
Corpus ID: 80334619
2006
2006
Excess salt and pepper hair treated with a combination of laser hair removal and topical eflornithine HCl.
Laura K Ganger
,
I. Hamzavi
Journal of Drugs in Dermatology
2006
Corpus ID: 36504971
A common problem among aging women, salt and pepper facial hair poses a significant psychosocial impact as well as a challenge…
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Review
2006
Review
2006
Current methods of treating hirsutism : review and a 3-month pilot study with topiCal antiandrogen fluridil
Kučerová
,
Fiuraskova
,
Hajduch
,
Brychtová
,
Seligson
,
SOvAK
2006
Corpus ID: 26557792
Hirsutism (H) is defined as an excessive male-pattern hair growth in women. H is caused by androgen excess or hypersensitivity of…
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2005
2005
NEW INDICATIONS Ertapenem for Foot Infections in Diabetes without Osteomyelitis
2005
Corpus ID: 35956716
714 P&T® • December 2005 • Vol. 30 No. 12 NEW DRUGS Eflornithine for Excess Facial Hair in Women Barrier Therapeutics has…
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1982
1982
Relationship of ornithine decarboxylase activity to HCG induced androgen production by rabbit testis
E. Younglai
Experientia
1982
Corpus ID: 13136566
In the rabbit testicular ornithine decarboxylase activity and androgen content as well as serum androgens were increased 4 h…
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