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Ropivacaine: an update of its use in regional anaesthesia.
TLDR
Ropivacaine is a well tolerated regional anaesthetic with an efficacy broadly similar to that of bupvacaine, however, it may be a preferred option because of its reduced CNS and cardiotoxic potential and its lower propensity for motor block. Expand
Fluvoxamine. An updated review of its use in the management of adults with anxiety disorders.
TLDR
Fluvoxamine has demonstrated short term efficacy in the treatment of OCD, panic disorder, social phobia, PTSD and in a range of obsessive-compulsive spectrum disorders and appears to have a better tolerability profile. Expand
Candesartan cilexetil. A review of its use in essential hypertension.
TLDR
Once daily candesartan cilexetil is effective and well tolerated when used once daily (as monotherapy or in combination with other antihypertensive agents) in patients with mild, moderate or severe hypertension. Expand
Topical Eflornithine
TLDR
In clinical studies in women with excessive, unwanted facial hair, eflornithine 15% cream was superior to placebo in reducing hair growth, as demonstrated by objective and subjective methods, after 2 to 8 weeks’ treatment. Expand
Oseltamivir: a review of its use in influenza.
TLDR
Oseltamivir is a well tolerated orally active neuraminidase inhibitor which significantly reduces the duration of symptomatic illness and hastens the return to normal levels of activity when initiated promptly in patients with naturally acquired influenza. Expand
Lercanidipine: a review of its use in hypertension.
TLDR
Lercanidipine is an effective and well tolerated once daily antihypertensive agent in patients with mild to moderate hypertension and will be particularly useful in patients not responding to, or intolerant of, anti Hypertensive agents from other drug classes. Expand
Losartan: a review of its use, with special focus on elderly patients.
TLDR
Results from the ELITE II (Evaluation of Losartan in the Elderly II) study indicate that there was no statistically significant difference between losartan and captopril in reducing overall deaths or in reducing sudden cardiac death and/or resuscitated cardiac arrest in patients with heart failure. Expand
Tropisetron: an update of its use in the prevention of chemotherapy-induced nausea and vomiting.
TLDR
Trisetron monotherapy is effective for the control of acute, and to a lesser extent delayed, nausea and vomiting in patients receiving moderately to severely emetogenic chemotherapy and the combination of dexamethasone and tropisetron is more effective than monotherapy. Expand
Trimetazidine. A review of its use in stable angina pectoris and other coronary conditions.
TLDR
Trimetazidine is an effective and well tolerated anti-ischaemic agent which, in addition to providing symptom relief and functional improvement in patients with angina pectoris, has a cytoprotective action during ischaemia. Expand
Midodrine. A review of its therapeutic use in the management of orthostatic hypotension.
TLDR
Oral midodrine significantly increases 1-minute standing systolic blood pressure compared with placebo and improves standing time and energy level and clinical symptoms of orthostatic hypotension including dizziness, light-headedness and syncope. Expand
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