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Eccrine dermal cylindroma

Known as: Cylindroma of Skin, Dermal Eccrine Cylindroma, Ancell-Spiegler cylindromas 
A benign sweat gland neoplasm usually occurring in the scalp or the face. It may present as solitary or multiple papular or nodular lesions. It may… 
National Institutes of Health

Related topics

Related topics

22 relations
Adenoid Cystic CarcinomaAutosomal dominant inheritanceBrooke-Spiegler syndromeCYLD gene

Narrower (1)

Familial multiple trichoepitheliomata

Broader (2)

Neoplastic Syndromes, HereditarySkin Neoplasms

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.
Review
2009
Review
2009
Update of cylindromatosis gene (CYLD) mutations in Brooke‐Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling
Germline mutations in the cylindromatosis (CYLD) gene have been described in families with cylindromas, trichoepitheliomas, and… 
Highly Cited
2006
Highly Cited
2006
Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.
Cylindromatosis (CYLD) is a deubiquitinating enzyme that is altered in patients with familial cylindromatosis, a condition… 
Highly Cited
2006
Highly Cited
2006
CYLD mutations underlie Brooke–Spiegler, familial cylindromatosis, and multiple familial trichoepithelioma syndromes
Brooke–Spiegler syndrome (BSS), familial cylindromatosis (FC), and multiple familial trichoepithelioma (MFT), originally… 
Highly Cited
2005
Highly Cited
2005
Dissection of the Inflammatory Bowel Disease Transcriptome Using Genome-Wide cDNA Microarrays
Background The differential pathophysiologic mechanisms that trigger and maintain the two forms of inflammatory bowel disease… 
Highly Cited
2005
Highly Cited
2005
Mutations in the CYLD gene in Brooke-Spiegler syndrome, familial cylindromatosis, and multiple familial trichoepithelioma: lack of genotype-phenotype correlation.
Brooke-Spiegler syndrome (BSS), familial cylindromatosis (FC), and multiple familial trichoepithelioma (MFT), originally… 
Highly Cited
1996
Highly Cited
1996
The gene for multiple familial trichoepithelioma maps to chromosome 9p21.
Multiple familial trichoepithelioma (MFT) is an autosomal dominant skin disease characterized by the presence of many small… 
Highly Cited
1995
Highly Cited
1995
Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12–q13: evidence for its role as a tumour suppressor gene
The human skin is a complex organ composed of the surface epidermis, the subjacent dermis (in which blood vessels, lymphatics and… 
Highly Cited
1990
Highly Cited
1990
Basal cell adenocarcinomas of the major salivary glands.
Highly Cited
1980
Highly Cited
1980
Sweat‐gland carcinomas: prognosis related to histological type
A series of 10 sweat‐gland carcinomas is reported. The ages of the patients at presentation ranged from 12 to 79 years. Three of… 
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