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CYLD gene

Known as: USPL2, KIAA0849, CYLD 
This gene is involved in protein deubiquitination.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy. The understanding of its gene expression… Expand
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Highly Cited
2008
Highly Cited
2008
Background: Germ-line mutations in CYLD are found in patients with familial skin appendage tumours. The protein product functions… Expand
2007
2007
Protein phosphorylation regulates many aspects of cellular function, including cell proliferation, migration, and signal… Expand
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Highly Cited
2006
Highly Cited
2006
T cell receptor signaling is essential for the generation and maturation of T lymphocyte precursors. Here we identify the… Expand
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2006
2006
Abstract:  Brooke–Spiegler syndrome (BSS) is an autosomal dominant disease characterized by cylindromas, trichoepitheliomas and… Expand
Highly Cited
2004
Highly Cited
2004
Multiple familial trichoepithelioma (MFT) and familial cylindromatosis are two clinically distinct cancer syndromes. MFT patients… Expand
Highly Cited
2002
Highly Cited
2002
The ubiquitin (Ub)-proteasome system includes a large family of deubiquitinating enzymes (DUBs). Many members are assigned to… Expand
Highly Cited
2002
Highly Cited
2002
Familial cylindromatosis (turban tumor syndrome; Brooke-Spiegler syndrome) (OMIM numbers 123850, 132700, 313100, and 605041) is a… Expand
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Highly Cited
2002
Highly Cited
2002
We describe the morphology and comparative genomic hybridization findings in a tumor for which we propose the term… Expand
Highly Cited
2000
Highly Cited
2000
Familial cylindromatosis is an autosomal dominant genetic predisposition to multiple tumours of the skin appendages. The… Expand
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