• Publications
  • Influence
Pemphigoid gestationis: current insights into pathogenesis and treatment.
  • K. Semkova, M. Black
  • Biology, Medicine
    European journal of obstetrics, gynecology, and…
  • 1 August 2009
Polymorphic eruption of pregnancy: clinicopathology and potential trigger factors in 181 patients
TLDR
Polymorphic eruption of pregnancy is the most common specific dermatosis of pregnancy, however, its clinical characterization is controversial and its pathogenesis uncertain.
Lichen sclerosus et atrophicus and autoimmunity—a study of 350 women
A study of autoimmune related phenomena in 350 women with histologically confirmed lichen sclerosus et atrophicus revealed that 21.5% had one or more autoimmune related diseases, 21% had one or more
Bullous pemphigoid antigen II (BP180) and its soluble extracellular domains are major autoantigens in mucous membrane pemphigoid: the pathogenic relevance to HLA class II alleles and disease severity
TLDR
This work has confirmed that MMP is a chronic autoimmune subepithelial blistering disease associated with circulating IgG and/or IgA autoantibodies against several basement membrane zone antigens.
A study of desmoglein 1 autoantibodies in pemphigus vulgaris: racial differences in frequency and the association with a more severe phenotype
TLDR
Data suggest that the presence of Dsg1 antibodies is predictive of a potentially more severe disease and that genetic factors may determine the Dsg antibody profile.
Allelic heterogeneity of dominant and recessive COL7A1 mutations underlying epidermolysis bullosa pruriginosa.
TLDR
The molecular pathology in patients with the distinctive clinical features of epidermolysis bullosa pruriginosa is heterogeneous and it is suggested that other factors, in addition to the inherent COL7A1 mutation(s), may be responsible for an epidesis bullosaPrurigo nodules phenotype.
The specific dermatoses of pregnancy.
  • R. Holmes, M. Black
  • Medicine
    Journal of the American Academy of Dermatology
  • 1 March 1983
Collagen XVII/BP180: a collagenous transmembrane protein and component of the dermoepidermal anchoring complex
TLDR
In vivo and in vitro studies provide evidence for a pathogenic role of these autoantibodies, and suggest that the serum level and epitope specificity of these antibodies influences disease severity and phenotype.
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