CYLD protein, human

Known as: Ubiquitin Thioesterase CYLD, Ubiquitin Specific Peptidase Like 2, Ubiquitin Carboxyl-Terminal Hydrolase CYLD 
Ubiquitin carboxyl-terminal hydrolase CYLD (956 aa, ~107 kDa) is encoded by the human CYLD gene. This protein is involved in the mediation of protein… (More)

Topic mentions per year

Topic mentions per year

2000-2018
0204020002018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Microtubules are dynamic structures that are crucially involved in a variety of cellular activities. The dynamic properties and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Caspase 8 initiates apoptosis downstream of TNF death receptors by undergoing autocleavage and processing the executioner caspase… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
A transient inflammatory signal can initiate an epigenetic switch from nontransformed to cancer cells via a positive feedback… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
It was previously shown that the NF-κB pathway is downstream of oncogenic Notch1 in T cell acute lymphoblastic leukemia (T-ALL… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Mutations involving the nuclear factor-kappaB (NF-kappaB) pathway are present in at least 17% of multiple myeloma (MM) tumors and… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
On detecting viral RNAs, the RNA helicase retinoic acid-inducible gene I (RIG-I) activates the interferon regulatory factor 3… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Activation of NF-kappaB has been noted in many tumor types, however only rarely has this been linked to an underlying genetic… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
T cell receptor signaling is essential for the generation and maturation of T lymphocyte precursors. Here we identify the… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Familial cylindromatosis is an autosomal dominant predisposition to tumours of skin appendages called cylindromas. Familial… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
NF-kappaB transcription factors have key roles in inflammation, immune response, oncogenesis and protection against apoptosis. In… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?