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CYLD protein, human
Known as:
Ubiquitin Thioesterase CYLD
, Ubiquitin Specific Peptidase Like 2
, Ubiquitin Carboxyl-Terminal Hydrolase CYLD
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Ubiquitin carboxyl-terminal hydrolase CYLD (956 aa, ~107 kDa) is encoded by the human CYLD gene. This protein is involved in the mediation of protein…
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National Institutes of Health
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Related topics
Related topics
15 relations
Ancell-Spiegler cylindromas
CYLD gene
Cysteine Protease Genes
Deubiquitination
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Broader (1)
Tumor Suppressor Proteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
TRAF3 and CYLD Gene Defects in HPV-Associated Head and Neck Cancer: Biomarker of Response and Indicator of Targets for New Therapies
N. Issaeva
,
B. Burtness
,
W. Yarbrough
2018
Corpus ID: 55779651
The incidence of HPV-associated (HPV+) Head and Neck Squamous Cell Carcinomas (HNSCC) has dramatically increased over the last 2…
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2017
2017
The B-box module of CYLD is responsible for its intermolecular interaction and cytoplasmic localization
Songbo Xie
,
Miao Chen
,
+6 authors
Min Liu
OncoTarget
2017
Corpus ID: 54489835
The tumor suppressor protein cylindromatosis (CYLD), as a microtubule-associated deubiquitinase, plays a pivotal role in a wide…
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2016
2016
A Case Report of Multiple Cylindroma with Immunohistochemical Features
N. Watanabe
,
K. Kawase
,
+4 authors
Takuji Tanaka
2016
Corpus ID: 44202612
Cylindroma is a benign skin appendageal tumor arising from pluripotent stem cells in the follicle. Multiple cylindroma…
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2016
2016
Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice
J. Ran
,
Fan Yu
,
+5 authors
Min Liu
OncoTarget
2016
Corpus ID: 14856725
Cilia are present in most vertebrate tissues with a wide variety of functions, and abnormalities of cilia are linked to numerous…
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2016
2016
MiR-424-5 p promotes cell invasion and migration by targeting CYLD in human pancreatic cancer
Xiao Xu
,
Wei Yan
,
+6 authors
Zhou
2016
Corpus ID: 52242046
The effect and mechanism of miR-424-5p on the invasion and migration of human pancreatic cancer is unknown. Quantitative real…
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2013
2013
A Reporter Screen in a Human Haploid Cell Line Identifies CYLD as a Constitutive Inhibitor of NFB Citation
Clarissa C. Lee
,
J. Carette
,
T. Brummelkamp
,
H. Ploegh
2013
Corpus ID: 64360205
The development of forward genetic screens in human haploid cells has the potential to transform our understanding of the genetic…
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2011
2011
Recurrent CYLD nonsense mutation associated with a severe, disfiguring phenotype in an African American family with multiple familial trichoepithelioma.
K. Linos
,
J. Schwartz
,
D. Kazakov
,
T. Vaněček
,
J. Carlson
American journal of dermatopathology
2011
Corpus ID: 35469073
To the Editor:Recently, Kazakov et al1 performed a clinicopathologic and genotypic analysis on a series of 16 patients suffering…
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Review
2011
Review
2011
CYLD (cylindromatosis (turban tumor syndrome))
G. Courtois
2011
Corpus ID: 86435937
Review on CYLD (cylindromatosis (turban tumor syndrome)), with data on DNA, on the protein encoded, and where the gene is…
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2009
2009
CYLD expression in benign , malignant and metastatic lesions of colorectal epithelium and its prognostic role in colorectal carcinoma
Hongying Zhao
,
Feng Xu
,
M. Jin
,
G. An
,
Guosheng Feng
2009
Corpus ID: 29915044
Dysregulation of the cylindromatosis (CYLD) gene has been involved in various cancer entities, including colorectal carcinoma…
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2008
2008
Supplemental Data The Structure of the CYLD USP Domain Explains Its Specificity for Lys 63-Linked Polyubiquitin and Reveals a B Box Module
D. Komander
,
C. Lord
,
+4 authors
D. Barford
2008
Corpus ID: 3759214