Neoplastic Syndromes, Hereditary

Known as: Hereditary Neoplastic Syndromes, Syndromes, Hereditary Cancer, Familial Tumor Syndrome 
The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1939-2018
05010019392017

Papers overview

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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To investigate the potential contribution of germline sequence alterations in the BAP1 gene in uveal melanoma (UM… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Genetic testing for hereditary cancer syndromes contributes to the medical management of patients who may be at… (More)
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Highly Cited
2006
Highly Cited
2006
Epimutations in the germline, such as methylation of the MLH1 gene, may contribute to hereditary cancer syndrome in human, but… (More)
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Highly Cited
2004
Highly Cited
2004
Germ-line mutations inactivating BRCA2 predispose to cancer. BRCA2-deficient cells exhibit alterations in chromosome number… (More)
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Highly Cited
2001
Highly Cited
2001
von Hippel-Lindau (VHL) disease is a pleomorphic familial tumor syndrome that is characterized by the development of highly… (More)
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Highly Cited
2001
Highly Cited
2001
von Hippel-Lindau (VHL) disease is a hereditary cancer syndrome caused by germ line mutation of the von Hippel-Lindau tumor… (More)
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Highly Cited
2000
Highly Cited
2000
von Hippel–Lindau (VHL) disease is a hereditary cancer syndrome that is characterized by the development of multiple vascular… (More)
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Highly Cited
2000
Highly Cited
2000
The von Hippel-Lindau tumor suppressor protein (pVHL) has emerged as a key factor in cellular responses to oxygen availability… (More)
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Highly Cited
1999
Highly Cited
1999
Cancer cell genomes contain alterations beyond known etiologic events, but their total number has been unknown at even the order… (More)
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Highly Cited
1993
Highly Cited
1993
Mutations in the human APC gene caused various familial colon cancer syndromes. The Multiple intestinal neoplasia (Min) mouse… (More)
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