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ETS2 gene

Known as: ETS proto-oncogene 2, transcription factor, ETS2, ETS2 INTRONIC TRANSCRIPT 
This gene is involved in transcriptional activation and skeletal development.
National Institutes of Health

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7 relations
ETS2 ProteinHomo sapiensTranscriptional ActivationTranscriptional Regulation

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ETS2 wt Allele

Papers overview

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Highly Cited
2011
Highly Cited
2011
Ets2 Determines the Inflammatory State of Endothelial Cells in Advanced Atherosclerotic Lesions
Rationale: Neovascularization is required for embryonic development and plays a central role in diseases in adults. In… 
Highly Cited
2009
Highly Cited
2009
Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.
The ras/Raf/Mek/Erk pathway plays a central role in coordinating endothelial cell activities during angiogenesis. Transcription… 
Highly Cited
2008
Highly Cited
2008
Ets2 Maintains hTERT Gene Expression and Breast Cancer Cell Proliferation by Interacting with c-Myc*
Human telomerase reverse transcriptase (hTERT) underlies cancer cell immortalization, and the expression of hTERT is regulated… 
Highly Cited
2004
Highly Cited
2004
Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells.
Ets2 is a member of the Ets family of transcription factors that in humans comprise 25 distinct members. Various Ets-domain… 
Highly Cited
2003
Highly Cited
2003
Ets2-Dependent Stromal Regulation of Mouse Mammary Tumors
ABSTRACT The Ets2 transcription factor is regulated by mitogen-activated protein (MAP) kinase phosphorylation of a single… 
Highly Cited
2001
Highly Cited
2001
Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity
Cdk10 is a Cdc2-related kinase that may play a role in regulating the G2/M phase of the cell cycle. However little is known about… 
Review
2000
Review
2000
Ets transcription factors and targets in osteogenesis
Bone formation in vivo is a complex phenomenon whereby recruitment and replication of mesenchymal precursors of osteoblasts… 
Highly Cited
1999
Highly Cited
1999
The Ets2 Transcription Factor Inhibits Apoptosis Induced by Colony-Stimulating Factor 1 Deprivation of Macrophages through a Bcl-xL-Dependent Mechanism
ABSTRACT Bcl-xL, a member of the Bcl-2 family, inhibits apoptosis, and its expression is regulated at the transcriptional level… 
Highly Cited
1996
Highly Cited
1996
Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice
EXPRESSION of Ets2, a proto-oncogene1 and transcription factor2–5, occurs in a variety of cell types6. During murine development… 
Highly Cited
1996
Highly Cited
1996
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2
The Ras oncogene products regulate the expression of genes in transformed cells, and members of the Ets family of transcription… 
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