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Nestin expression – a property of multi-lineage progenitor cells?
- C. Wiese, A. Rolletschek, +6 authors A. Wobus
- Biology, Medicine
- Cellular and Molecular Life Sciences CMLS
- 1 October 2004
Abstract.Tissue-specific progenitor cells are characterized by proliferation and differentiation, but, in contrast to embryonic stem (ES) cells, have limited capacities for self-renewal and no… Expand
AGEMAP: A Gene Expression Database for Aging in Mice
We present the AGEMAP (Atlas of Gene Expression in Mouse Aging Project) gene expression database, which is a resource that catalogs changes in gene expression as a function of age in mice. The AGEMAP… Expand
Embryonic stem cells: prospects for developmental biology and cell therapy.
Stem cells represent natural units of embryonic development and tissue regeneration. Embryonic stem (ES) cells, in particular, possess a nearly unlimited self-renewal capacity and developmental… Expand
Differentiation of Pluripotent Embryonic Stem Cells Into Cardiomyocytes
- K. Boheler, J. Czyz, D. Tweedie, H. Yang, S. Anisimov, A. Wobus
- Medicine, Biology
- Circulation research
- 9 August 2002
Abstract— Embryonic stem (ES) cells have been established as permanent lines of undifferentiated pluripotent cells from early mouse embryos. ES cells provide a unique system for the genetic… Expand
Local Control Models of Cardiac Excitation–Contraction Coupling
- M. Stern, L. Song, +4 authors E. Ríos
- Medicine, Chemistry
- The Journal of general physiology
- 1 March 1999
In cardiac muscle, release of activator calcium from the sarcoplasmic reticulum occurs by calcium- induced calcium release through ryanodine receptors (RyRs), which are clustered in a dense, regular,… Expand
Embryonic stem cells as a model to study cardiac, skeletal muscle, and vascular smooth muscle cell differentiation.
A Mass Spectrometric-Derived Cell Surface Protein Atlas
Cell surface proteins are major targets of biomedical research due to their utility as cellular markers and their extracellular accessibility for pharmacological intervention. However, information… Expand
Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure.
A decrease in the myocardial level of the mRNA encoding the Ca2(+)-ATPase of the sarcoplasmic reticulum (SR) has been recently reported during experimental cardiac hypertrophy and failure. To… Expand
Cardiomyocytes purified from differentiated embryonic stem cells exhibit characteristics of early chamber myocardium.
- A. C. Fijnvandraat, A. V. van Ginneken, +4 authors A. Moorman
- Medicine, Biology
- Journal of molecular and cellular cardiology
- 1 December 2003
Mouse embryonic stem (ES) cells easily differentiate towards the cardiac lineage making them suitable as an in vitro model to study cardiogenesis and as a potential source of transplantable cells. In… Expand
Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors.
Prominin-1/CD133 is a plasma membrane marker found in several types of somatic stem cells, including hematopoietic and neural stem cells. To study its role during development and with… Expand