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ETS2 wt Allele

Known as: ETS2, v-ets Avian Erythroblastosis Virus E26 Oncogene Homolog 2, v-ETS Erythroblastosis Virus E26 Oncogene Homolog 2 (Avian) wt Allele 
The human ETS2 wild-type allele is located in the vicinity of 21q22 and is approximately 19 kb in length. This allele, which encodes protein C-ets-2… 
National Institutes of Health

Related topics

Related topics

9 relations
21q22.2ETS2 ProteinHomo sapiensMacrophage Differentiation Pathway
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Broader (1)

ETS2 gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
Transcriptional regulation of miR-196b by ETS2 in gastric cancer cells
E26 transformation-specific sequence (ETS)-2 is a transcriptional modulator located on chromosome 21, alterations in its… 
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Highly Cited
2010
Highly Cited
2010
An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.
Tumor-associated macrophages (TAM) are implicated in breast cancer metastasis, but relatively little is known about the… 
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Highly Cited
2004
Highly Cited
2004
Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells.
Ets2 is a member of the Ets family of transcription factors that in humans comprise 25 distinct members. Various Ets-domain… 
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Highly Cited
2003
Highly Cited
2003
Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis
Down syndrome (trisomy 21) neurons display an increased rate of apoptosis in vitro. The genes on chromosome 21 that mediate this… 
Highly Cited
2000
Highly Cited
2000
Involvement of Ets transcription factors and targets in osteoblast differentiation and matrix mineralization.
The osteoblast-like MC3T3-E1 cell line provides an excellent in vitro model of bone development. This system undergoes three… 
Highly Cited
1999
Highly Cited
1999
Regulation of the Human Interleukin-5 Promoter by Ets Transcription Factors
Interleukin-5 (IL-5), expressed primarily by type-2 T helper (Th2) cells, plays an important role in the development of allergic… 
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Highly Cited
1999
Highly Cited
1999
The Ets2 Transcription Factor Inhibits Apoptosis Induced by Colony-Stimulating Factor 1 Deprivation of Macrophages through a Bcl-xL-Dependent Mechanism
ABSTRACT Bcl-xL, a member of the Bcl-2 family, inhibits apoptosis, and its expression is regulated at the transcriptional level… 
Highly Cited
1998
Highly Cited
1998
Defective trophoblast function in mice with a targeted mutation of Ets2.
Members of the Ets family of transcription factors mediate transcriptional responses of multiple signaling pathways in diverse… 
Highly Cited
1997
Highly Cited
1997
The Ets Transcription Factors Interact with Each Other and with the c-Fos/c-Jun Complex via Distinct Protein Domains in a DNA-dependent and -independent Manner*
The transcription factors Fos, Jun, and Ets regulate the expression of human stromelysin-1 and collagenase-1 genes. Recently, we… 
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1994
1994
Myb and Ets related transcription factors are required for activity of the human lck type I promoter.
The lck gene, which encodes a lymphoid-specific Src family tyrosine kinase, is transcribed from two promoters that are… 
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