21q22.2

A chromosome band present on 21q
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Prostate cancer is significantly more common in Western men than in Asian men, but the basis for this difference remains unknown… (More)
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Highly Cited
2009
Highly Cited
2009
Gene fusions play a critical role in cancer progression. The mechanisms underlying their genesis and cell type specificity are… (More)
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Highly Cited
2006
Highly Cited
2006
Prostate cancer is a common and clinically heterogeneous disease with marked variability in progression. The recent… (More)
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Highly Cited
2006
Highly Cited
2006
Among the various phenotypes seen in Down syndrome (DS), mental retardation is the most common and most debilitating condition… (More)
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Highly Cited
1998
Highly Cited
1998
Down syndrome (DS), a major cause of mental retardation, is characterized by subtle abnormalities of cortical neuroanatomy… (More)
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Highly Cited
1997
Highly Cited
1997
Using Down syndrome as a model for complex trait analysis, we sought to identify loci from chromosome 21q22.2 which, when present… (More)
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Review
1997
Review
1997
Libraries of the mammalian genome have generally been propagated in single cells and have been used for gene discovery through in… (More)
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1996
1996
We identified and cloned a novel 9,078-bp cDNA, designated TPRDI, from the Down syndrome-critical region by exon trapping. The… (More)
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1995
1995
Libraries of the entire human genome, or regions of the genome, have been made in bacteria, yeast, and somatic cells. We have… (More)
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1984
1984
A deleted chromosome 21 is reported in a mentally retarded girl with prominent occiput, high nasal bridge, downward slanting eyes… (More)
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