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ETP-46321

National Institutes of Health

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2 relations

Broader (2)

ImidazolesPyrazines

Papers overview

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2017
2017
Generation of tricyclic imidazo[1,2-a]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy.
2017
2017
Identification of novel PI3K inhibitors through a scaffold hopping strategy.
2016
2016
ETP-46321, a dual p110α/δ class IA phosphoinositide 3-kinase inhibitor modulates T lymphocyte activation and collagen-induced arthritis.
2012
2012
Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases
SummaryInhibitors of PI3K signaling are of great therapeutic interest in oncology. The phosphoinositide-3-kinase signaling… 
2010
2010
134 Biological characterization of ETP-46321 a potent and selective phosphoinositide-3-kinase inhibitor with antitumor activity
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