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ERCC6 protein, human

Known as: Cockayne Syndrome B Repair Protein, Cockayne Syndrome Protein CSB, ATP-Dependent Helicase ERCC6 
DNA excision repair protein ERCC-6 (1493 aa, ~168 kDa) is encoded by the human ERCC6 gene. This protein plays a role in transcription-coupled DNA… 
National Institutes of Health

Related topics

Related topics

13 relations
Adenosine TriphosphatasesCell NucleusCockayne SyndromeDNA Repair

Broader (2)

DNA HelicasesDNA Repair Enzymes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Let-7c-5p inhibits cell proliferation and induces cell apoptosis by targeting ERCC6 in breast cancer.
In this study, we found that let-7c-5p expression was clearly downregulated in breast cancer tissues compared with that of… 
2016
2016
A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair
Abstract Cockayne syndrome B (CSB), best known for its role in transcription-coupled nucleotide excision repair (TC-NER… 
Highly Cited
2011
Highly Cited
2011
Chronic exposure to arsenic causes increased cell survival, DNA damage, and increased expression of mitochondrial transcription factor A (mtTFA) in human prostate epithelial cells.
Arsenic is a known carcinogen, and its exposure is associated with cancers in multiple target organs including the prostate… 
2011
2011
RAR&bgr;2 gene methylation level in the circulating DNA from blood of patients with lung cancer
Alterations in the patterns of DNA methylation are among the earliest and most common events in tumorigenesis. Epigenetic changes… 
Highly Cited
2009
Highly Cited
2009
Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by polymorphisms in five other nucleotide excision repair…
Laryngeal cancer is known to be associated with smoking and high alcohol consumption. Nucleotide excision repair (NER) plays a… 
Highly Cited
2008
Highly Cited
2008
A novel single nucleotide polymorphism in ERCC6 gene is associated with oral cancer susceptibility in Taiwanese patients.
Review
2006
Review
2006
Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes
One of the many potential uses of the HapMap project is its application to the investigation of complex disease aetiology among a… 
Highly Cited
1996
Highly Cited
1996
Functional analysis of the DNA-stimulated ATPase domain of yeast SWI2/SNF2.
The yeast SWI2/SNF2 polypeptide is a subunit of the SWI/SNF protein complex that is required for many transcriptional activators… 
1996
1996
Mismatch repair mutants in yeast are not defective in transcription-coupled DNA repair of UV-induced DNA damage.
Transcription-coupled repair, the targeted repair of the transcribed strands of active genes, is defective in bacteria, yeast… 
Highly Cited
1993
Highly Cited
1993
Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B.
The human repair gene ERCC6--a presumed DNA (or RNA) helicase--has recently been found to function specifically in preferential… 
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