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ERCC2 wt Allele

Known as: Excision-Repair, Complementing Defective, In Chinese Hamster, 2 Gene, TTD, Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (Xeroderma Pigmentosum D) wt Allele 
Human ERCC2 wild-type allele is located in the vicinity of 19q13.3 and is approximately 19 kb in length. This allele, which encodes TFIIH basal… 
National Institutes of Health

Related topics

Related topics

12 relations
19q13.3Cell Cycle ControlCerebrooculofacioskeletal Syndrome 1Cockayne Syndrome

Broader (1)

ERCC2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
DNA repair protein levels vis-à-vis anticancer drug resistance in the human tumor cell lines of the National Cancer Institute drug screening program
Nucleotide excision repair (NER) is a multi-enzyme DNA repair pathway in eukaryotes. Several NER genes in this pathway including… 
Highly Cited
1998
Highly Cited
1998
The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication.
Highly Cited
1994
Highly Cited
1994
Altered DNA ligase III activity in the CHO EM9 mutant.
Highly Cited
1988
Highly Cited
1988
Induction and rejoining of gamma-ray-induced DNA single- and double-strand breaks in Chinese hamster AA8 cells and in two radiosensitive clones.
The induction and rejoining of gamma-ray-induced DNA strand breaks were measured in a Chinese hamster ovary cell line, AA8, and… 
1987
1987
Induction and repair of DNA single-strand breaks in EM9 mutant CHO cells treated with hydrogen peroxide.
Highly Cited
1987
Highly Cited
1987
Recovery from sublethal and potentially lethal damage in an X-ray-sensitive CHO cell.
It has been suggested that DNA strand breaks are the molecular lesions responsible for radiation-induced lethality and that their… 
1986
1986
Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line.
Highly Cited
1984
Highly Cited
1984
DNA-strand breaks associated with halogenated pyrimidine incorporation.
Highly Cited
1984
Highly Cited
1984
Rapid detection of DNA-damaging agents using repair-deficient CHO cells.
Highly Cited
1983
Highly Cited
1983
The relationship between sister-chromatid exchange and perturbations in DNA replication in mutant EM9 and normal CHO cells.
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