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ERCC2 wt Allele

Known as: Excision-Repair, Complementing Defective, In Chinese Hamster, 2 Gene, TTD, Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (Xeroderma Pigmentosum D) wt Allele 
Human ERCC2 wild-type allele is located in the vicinity of 19q13.3 and is approximately 19 kb in length. This allele, which encodes TFIIH basal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
UNLABELLED Cisplatin-based chemotherapy is the standard of care for patients with muscle-invasive urothelial carcinoma… Expand
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Highly Cited
2011
Highly Cited
2011
Base excision repair (BER) represents the most important repair pathway of endogenous DNA lesions. Initially, a base damage is… Expand
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Highly Cited
2006
Highly Cited
2006
Environmental carcinogens contained in air pollution, such as polycyclic aromatic hydrocarbons, aromatic amines or N-nitroso… Expand
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Highly Cited
2004
Highly Cited
2004
PURPOSE Platinum agents cause DNA cross-linking and oxidative damage. Genetic polymorphisms of DNA repair genes are associated… Expand
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Highly Cited
2004
Highly Cited
2004
We analysed the associations between genetic polymorphisms in genes coding for DNA repair enzymes XPD (exon 23 A --> C, K751Q… Expand
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Highly Cited
2004
Highly Cited
2004
A limited number of genes have been identified that explain heritable risks of breast cancer (BC). We searched for low-penetrant… Expand
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Highly Cited
1995
Highly Cited
1995
The human DNA repair protein XRCC1 was overexpressed as a histidine-tagged polypeptide (denoted XRCC1-His) in Escherichia coli… Expand
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Highly Cited
1994
Highly Cited
1994
XRCC1, the human gene that fully corrects the Chinese hamster ovary DNA repair mutant EM9, encodes a protein involved in the… Expand
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Highly Cited
1990
Highly Cited
1990
We describe the cloning and function of the human XRCC1 gene, which is the first mammalian gene isolated that affects cellular… Expand
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Highly Cited
1982
Highly Cited
1982
A mutant of CHO cells (strain EM9) previously isolated on the basis of hypersensitivity to killing by ethyl methanesulfonate (EMS… Expand
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