ERCC2 gene

Known as: TFIIH basal transcription factor complex helicase XPB subunit, ERCC2, EXCISION REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 2 
This gene is involved in nucleotide excision repair and corrects sensitivity to UV radiation and defective nucleotide excision repair in xeroderma… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2018
010203019652018

Papers overview

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Highly Cited
2005
Highly Cited
2005
Homologous recombination is vital to repair fatal DNA damage during DNA replication. However, very little is known about the… (More)
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Highly Cited
2004
Highly Cited
2004
We investigated the association of urinary bladder cancer with genetic polymorphisms in the xeroderma pigmentosum complementation… (More)
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Highly Cited
2002
Highly Cited
2002
Myelin inhibitors of axonal regeneration, like Nogo and MAG, block regrowth after injury to the adult CNS. While a GPI-linked… (More)
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Highly Cited
2000
Highly Cited
2000
Polymorphisms in several DNA repair genes have recently been identified, but little is known about their phenotypic significance… (More)
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Highly Cited
2000
Highly Cited
2000
DNA repair capacity is central in maintaining normal cellular functions. Variants of several DNA repair genes,including the… (More)
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Highly Cited
1997
Highly Cited
1997
The transcription/DNA repair factor TFIIH consists of nine subunits, several exhibiting known functions: helicase/ATPase, kinase… (More)
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Highly Cited
1994
Highly Cited
1994
XRCC1, the human gene that fully corrects the Chinese hamster ovary DNA repair mutant EM9, encodes a protein involved in the… (More)
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Highly Cited
1993
Highly Cited
1993
XERODERMA pigmentosum (XP), a genetically heterogeneous human disease, results from a defect in nucleotide excision repair of… (More)
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Highly Cited
1990
Highly Cited
1990
We describe the cloning and function of the human XRCC1 gene, which is the first mammalian gene isolated that affects cellular… (More)
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Highly Cited
1982
Highly Cited
1982
A mutant of CHO cells (strain EM9) previously isolated on the basis of hypersensitivity to killing by ethyl methanesulfonate (EMS… (More)
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