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ERBB3 protein, human

Known as: Receptor Tyrosine-Protein Kinase erbB3, ERBB3 Receptor Protein-Tyrosine Kinase, ERBB3 Protein 
Receptor tyrosine-protein kinase erbB3 (1342 aa, ~148 kDa) is encoded by the human ERBB3 gene. This protein plays a role in protein amino acid… 
National Institutes of Health

Related topics

Related topics

25 relations
Cell Differentiation processCell Growth RegulationCell ProliferationERBB2 Signaling Pathway

Broader (1)

ERBB3 Receptor Protein-Tyrosine Kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
The Role of c-erbB-2/HER2/neu in Breast Cancer Progression and Metastasis
  • S. Eccles
  • Journal of mammary gland biology and neoplasia
  • 2001
  • Corpus ID: 12457722
Gene amplification and/or overexpression of the c-erbB-2/HER2/neu tyrosine kinase are linked with poor prognosis in breast cancer… 
Highly Cited
2000
Highly Cited
2000
Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay.
We measured the expression of the type I growth factor receptor gene family [epidermal growth factor receptor (EGFR), c-erbB-2, c… 
Highly Cited
2000
Highly Cited
2000
Expression of c‐erbB receptors, heregulin and oestrogen receptor in human breast cell lines
Members of the c‐erbB family have been implicated in poor prognosis in breast cancer. Given the propensity for heterodimerisation… 
Highly Cited
2000
Highly Cited
2000
Nuclear expression of the c-erbB-4/HER-4 growth factor receptor in invasive breast cancers.
The prevalence and sites of expression of the c-erbB-4 receptor have been determined by immunocytochemical staining in a series… 
Highly Cited
1998
Highly Cited
1998
Expression of c-erbB3 protein in primary breast carcinomas.
Expression of c-erbB3 protein was investigated in 104 primary breast carcinomas comprising nine comedo ductal carcinoma in situ… 
Highly Cited
1998
Highly Cited
1998
Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein.
The role of protein tyrosine kinase activity in ErbB3-mediated signal transduction was investigated. ErbB3 was phosphorylated in… 
Highly Cited
1998
Highly Cited
1998
c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer
We examined c-erbB3 and c-erbB4 mRNA expression in 47 primary breast cancer samples by simultaneous RT–PCR and have investigated… 
Highly Cited
1994
Highly Cited
1994
Identification of c‐erbB‐3 binding sites for phosphatidylinositol 3′‐kinase and SHC using an EGF receptor/c‐erbB‐3 chimera.
c‐erbB‐3 is a member of the type I (EGF receptor‐related) family of growth factor receptors for which no ligand has been… 
Review
1992
Review
1992
The type 1 (EGFR-related) family of growth factor receptors and their ligands.
Highly Cited
1992
Highly Cited
1992
Expression of the c-erbB-3 protein in normal human adult and fetal tissues.
c-erbB-3 is a member of the type I family of growth factor receptors which includes the epidermal growth factor (EGF) receptor… 
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