ERBB3 Receptor Protein-Tyrosine Kinase

Known as: c-erbB-3 Protein, c erbB 3 Protein, Proto Oncogene Protein c erbB 3 
A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
ERBB3/HER3 is emerging as a molecular target for various cancers. HER3 is overexpressed and activated in a number of cancer types… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE Abnormal accumulation and dysregulation of the epidermal growth factor receptor family member HER3 is associated with the… (More)
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2011
2011
Multiscale modeling provides a powerful and quantitative platform for investigating the complexity inherent in intracellular… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE To compare the characteristics of deregulation of HER receptors and their ligands between primary tumor and corresponding… (More)
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2009
2009
Overexpression on plasma membrane of human epidermal growth factor receptor 2 (HER2) is reported in 25% to 30% of breast cancers… (More)
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Highly Cited
2008
Highly Cited
2008
Epidermal growth factor receptor (EGFR) and HER3 each form heterodimers with HER2 and have independently been implicated as key… (More)
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Highly Cited
2007
Highly Cited
2007
Oncogenic tyrosine kinases have proved to be promising targets for the development of highly effective anticancer drugs. However… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The androgen receptor (AR) is a ligand-dependent transcription factor that mediates gene expression and growth of normal… (More)
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2005
2005
In teleosts and amphibians, the proneuronal domains, which give rise to primary-motor, primary-inter and Rohon-Beard (RB) neurons… (More)
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1994
1994
c-erbB-3 protein expression was investigated immunohistochemically in a series of 97 malignant breast tumours using the… (More)
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