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Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County.
It is suggested that environmental factors in early life rather than in later life are important in the etiology of breast cancer and that later life events can substantially impact the likelihood of developing clinically detectable prostate cancer. Expand
Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the Japanese population.
It is suggested that the CYP1A1 polymorphism and its combination with GSTM1 may be associated with PCa susceptibility in the Japanese population. Expand
Geographic pathology of occult thyroid carcinomas
Thyroid glands obtained from patients in southeastern Canada, northeastern Japan, southern Poland, western Colombia, and from Japanese living in Hawaii were serially step‐sectioned and examinedExpand
Impact of genetic polymorphisms of 17‐hydroxylase cytochrome P‐450 (CYP17) and steroid 5α‐reductase type II (SRD5A2) genes on prostate‐cancer risk among the Japanese population
A case‐control study of 105 prostate‐cancer patients and 210 controls with benign prostatic hyperplasia is designed, suggesting a significant association between the CYP17 polymorphism and prostate‐ cancer risk among the Japanese. Expand
Geographic pathology of latent prostatic carcinoma
The results suggest that the prevalence of LIT tumors shows a race variation similar to the incidence of clinical carcinoma of the prostate, and that LNT tumors probably remain latent during the individual's life span. Expand
Genetic polymorphisms of hormone-related genes and prostate cancer risk in the Japanese population.
This pilot study showed that CYP1B1 and PR polymorphisms, alone or in combination, might be associated with prostate cancer risk and might have potential as a tool for identifying high-risk individuals. Expand
Diverticulosis and polyps of the large intestine. A necropsy study of hawaii japanese
Autopsy study of the colon of Hawaii Japanese indicates that, unlike native Japanese, diverticulosis and both adenomatous and hyperplastic polyps are very common in this population. This isExpand
Presence of ras oncogene mutations and human papillomavirus DNA in human prostate carcinomas.
The results suggest that ras gene mutations and HPV infections are relatively frequent, at least in prostate carcinoma of Japanese patients, and these two factors appear to be related to the progression of the tumor. Expand
Epigenetic Regulation of Androgen Receptor Gene Expression in Human Prostate Cancers
The results suggest that epigenetic regulations including CpG methylation and histone acetylation may play important roles in the regulation of the AR. Expand
Localization of a tumor suppressor gene associated with progression of human prostate cancer within a 1.2 Mb region of 8p22‐p21.3
High‐resolution deletion mapping in 46 prostate cancers suggests that inactivation of tumor suppressor genes on 8p plays an important role in the progression of prostate cancer. Expand