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EGLN1 wt Allele

Known as: Egl Nine Homolog 1 (C. elegans) wt Allele, HPH-2, PHD2 
Human EGLN1 wild-type allele is located in the vicinity of 1q42.1 and is approximately 61 kb in length. This allele, which encodes egl nine homolog 1… 
National Institutes of Health

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Related topics

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Broader (1)

EGLN1 gene
Egl Nine Homolog 1HomeostasisOxidation-Reduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Chronic kidney disease leads to hypoxia inducible factor-1alpha to hypoxia inducible factor-2alpha switch in the gastrocnemius muscle.
Hipoxia inducible factor-1 and HIF-2 are responsible for the adaptation of cell metabolism to hypoxia. Previously, a more severe… 
2012
2012
Prolyl Hydroxylase Domain 2 Protein Is a Strong Prognostic Marker in Human Gastric Cancer
Objective: According to recent research, prolyl hydroxylase domain 2 protein (PHD2) plays an important role in human… 
2010
2010
Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth.
2010
2010
Apicidin upregulates PHD2 prolyl hydroxylase gene expression in cervical cancer cells
It was recently reported that the reduced expression of hypoxia-inducible factor prolyl 4-hydroxylase PHD2 in human cancers… 
Highly Cited
2009
Highly Cited
2009
Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2.
Highly Cited
2008
Highly Cited
2008
The Biphasic Role of the Hypoxia-Inducible Factor Prolyl-4-Hydroxylase, PHD2, in Modulating Tumor-Forming Potential
Hypoxia is a common feature of solid tumors. The cellular response to hypoxic stress is controlled by a family of prolyl… 
2004
2004
Regulation of the SM-20 prolyl hydroxylase gene in smooth muscle cells.
2003
2003
Induction of SM‐20 in PC12 cells leads to increased cytochrome c levels, accumulation of cytochrome c in the cytosol, and caspase‐dependent cell death
Sympathetic neurons deprived of nerve growth factor (NGF) release cytochrome c into the cytosol and undergo caspase‐dependent… 
1999
1999
SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation.
SM-20 is a novel, evolutionarily conserved "early response" gene originally cloned from a rat aortic smooth muscle cell (SMC… 
Highly Cited
1994
Highly Cited
1994
Identification of a novel growth factor-responsive gene in vascular smooth muscle cells.
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