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E 7010

Known as: E-7010, E7010 
National Institutes of Health

Related topics

Related topics

3 relations
ABT751

Broader (2)

AminophenolsSulfonamides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Design, synthesis and evaluation of novel sulfonamides as potential anticancer agents
2008
2008
Inhibitors of Tubulin Assembly Identified through Screening a Compound Library
Tubulin is the proposed target for drugs against cancer and helminths and is also a validated target in kinetoplastid parasites… 
Highly Cited
2002
Highly Cited
2002
Profiling novel sulfonamide antitumor agents with cell-based phenotypic screens and array-based gene expression analysis.
A series of small molecules from sulfonamide-focused libraries have been evaluated in these laboratories to discover novel… 
Highly Cited
2002
Highly Cited
2002
Array-based structure and gene expression relationship study of antitumor sulfonamides including N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide and N-(3-chloro-7-indolyl)-1,4…
Compounds from sulfonamide-focused libraries have been evaluated in cell-based antitumor screens using the COMPARE analysis with… 
2001
2001
Novel sulfonate derivatives: potent antimitotic agents.
2000
2000
Effect of E7010 on liver metastasis and life span of syngeneic C57BL/6 mice bearing orthotopically transplanted murine Colon 38 tumor
Abstract. Purpose: E7010 is an orally active sulfonamide antitumor agent showing good activity against various subcutaneously… 
Highly Cited
1999
Highly Cited
1999
Evaluation of Antivascular and Antimitotic Effects of Tubulin Binding Agents in Solid Tumor Therapy
Tubulin binding agents (TBAs) reduce tumor perfusion and inhibit mitosis of tumor cells in solid tumors, but it is not clear… 
Highly Cited
1998
Highly Cited
1998
Phase I study of E7010
Abstract E7010 is a novel sulfonamide which was discovered using slow-growing colon 38 carcinoma cells as a screening model… 
1998
1998
Preferential Binding of E7010 to Murine β3‐Tubulin and Decreased β3‐Tubulin in E7010‐resistant Cell Lines
N‐[2‐[(4‐Hydroxyphenyl)amino]‐3‐pyridyl]‐4‐methoxybenzenesulfonamide (E7010) is a novel sulfonamide antimitotic agent, which is… 
Highly Cited
1997
Highly Cited
1997
Antitumor Activity of TZT‐1027, a Novel Doiastatin 10 Derivative
Dolastatin 10, a pentapeptide isolated from the marine mollusk Dolabella auricularia, has antitumor activity. TZT‐1027, a… 
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