Drug Resistance, Viral

Known as: Antiviral Drug Resistance, Antiviral Drug Resistances, Drug Resistances, Viral 
The ability of viruses to resist or to become tolerant to chemotherapeutic agents or antiviral agents. This resistance is acquired through gene… (More)
National Institutes of Health

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aspects of radiation effectsphysiological aspects

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Review
2013
Review
2013
HIV-1 reverse transcriptase and antiviral drug resistance. Part 2.
Structures of RT and its complexes combined with biochemical and clinical data help in illuminating the molecular mechanisms of… (More)
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Review
2010
Review
2010
Molecular genesis of drug-resistant and vaccine-escape HBV mutants.
A high rate of viral turnover, combined with an error-prone polymerase, results in a very high frequency of mutational events… (More)
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Highly Cited
2008
Highly Cited
2008
The antiviral drug selected hepatitis B virus rtA181T/sW172* mutant has a dominant negative secretion defect and alters the typical profile of viral rebound.
UNLABELLED The hepatitis B virus (HBV) mutation that encodes rtA181T is selected in the viral polymerase during antiviral drug… (More)
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Highly Cited
2008
Highly Cited
2008
Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure.
BACKGROUND/AIMS Recent clinical observations reported the occurrence of amino acid substitutions at position 181 of the HBV… (More)
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Highly Cited
2007
Highly Cited
2007
Predictors of incomplete adherence, virologic failure, and antiviral drug resistance among HIV-infected adults receiving antiretroviral therapy in Tanzania.
BACKGROUND Access to antiretroviral therapy is rapidly expanding in sub-Saharan Africa. Identifying the predictors of incomplete… (More)
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Review
2006
Review
2006
Antiviral drug resistance.
Almost 30 years ago it was proposed that the selection for antiviral drug resistance should be used as an indicator of antiviral… (More)
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Highly Cited
2005
Highly Cited
2005
Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).
Plant flavonoids are polyphenolic compounds, commonly found in vegetables, fruits and many food sources that form a significant… (More)
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Review
2003
Review
2003
Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality after hematopoietic stem cell transplantation… (More)
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Highly Cited
1998
Highly Cited
1998
Predicting and preventing the emergence of antiviral drug resistance in HSV-2
Genital herpes, caused by herpes simplex virus, is the most prevalent sexually transmitted disease worldwide. In many developing… (More)
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Review
1996
Review
1996
Viral dynamics of HIV: implications for drug development and therapeutic strategies.
The recent advances in our understanding of human immunodeficiency virus (HIV) burden, dynamics, and resistance provide an… (More)
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