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Drug Antagonism

Known as: Antagonism, Drug, Antagonisms, Drug, Drug Antagonisms 
Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a… 
National Institutes of Health

Related topics

Related topics

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Narcotic Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism.
Review
2009
Review
2009
Drug interactions and the evolution of antibiotic resistance
Large-scale, systems biology approaches now allow us to systematically map synergistic and antagonistic interactions between… 
Highly Cited
2001
Highly Cited
2001
Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo.
All-trans retinoic acid (tRA) and arsenic trioxide (As(2)O(3)) induce non-cross-resistant complete clinical remission in patients… 
Highly Cited
2000
Highly Cited
2000
No influence of adrenergic receptor polymorphisms on schizophrenia and antipsychotic response
Highly Cited
1987
Highly Cited
1987
Validation of the five-factor model of personality across instruments and observers.
  • R. McCraeP. Costa
  • Journal of Personality and Social Psychology
  • 1987
  • Corpus ID: 7893185
Two data sources--self-reports and peer ratings--and two instruments--adjective factors and questionnaire scales--were used to… 
Highly Cited
1969
Highly Cited
1969
A new kind of drug antagonism: evidence that agonists cause a molecular change in acetylcholine receptors.
The effects of various curare-like compounds on the contractile responses to carbachol and suxamethonium of thin strips of chick… 
Highly Cited
1967
Highly Cited
1967
Temperature changes produced by the injection of catecholamines and 5‐hydroxytryptamine into the cerebral ventricles of the conscious mouse
1. Changes in temperature were determined following injection of noradrenaline, adrenaline, isoprenaline, dopamine and 5… 
Highly Cited
1957
Highly Cited
1957
Nonequilibrium drug antagonism.
Numerous studies during the past decade have demonstrated that certain pharmacological antagonists act through a relatively… 
Highly Cited
1949
Highly Cited
1949
pAx and competitive drug antagonism.
  • H. Schild
  • British Journal of Pharmacology and Chemotherapy
  • 1949
  • Corpus ID: 28523159
In a recent paper Guarino and Bovet (1949) have studied the use of the measure pA for expressing intensity of drug antagonism. pA… 
Highly Cited
1947
Highly Cited
1947
pA, A NEW SCALE FOR THE MEASUREMENT OF DRUG ANTAGONISM
  • H. Schild
  • British Journal of Pharmacology and Chemotherapy
  • 1947
  • Corpus ID: 28346417
This is the first of a set of three papers in the Journal that were to transform the study of drug antagonism (see also Schild… 
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