Doxepin

Known as: 1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-, Doxepin [Chemical/Ingredient] 
A dibenzoxepin derivative and tricyclic antidepressant (TCA) with antipruritic, antidepressive and anxiolytic activities. Doxepin blocks the reuptake… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2018
010203019642018

Papers overview

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Highly Cited
2011
Highly Cited
2011
The biogenic amine histamine is an important pharmacological mediator involved in pathophysiological processes such as allergies… (More)
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2007
2007
STUDY OBJECTIVES To evaluate the efficacy and safety of doxepin 1, 3, and 6 mg in insomnia patients. DESIGN Adults (18-64 y… (More)
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2007
2007
It has been suggested that the polymorphism of the CYP2D6 gene can contribute to occurrence of fatal adverse effects. We… (More)
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2004
2004
Histamine H1-receptor (H1R) antagonists, or antihistamines, often induce sedative side effects when used for the treatment of… (More)
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2001
2001
BACKGROUND Over recent years, the use of antidepressants for the symptomatic treatment of insomnia has grown substantially, but… (More)
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2000
2000
AIMS To assess the analgesic efficacy of topical administration of 3.3% doxepin hydrochloride, 0.025% capsaicin and a combination… (More)
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1994
1994
BACKGROUND Atopic dermatitis is associated with severe pruritus for which effective topical treatment is lacking. As a potent H1… (More)
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1986
1986
Doxepin hydrochloride, a tricyclic antidepressant, was evaluated in a double-blind, placebo-controlled crossover trial for the… (More)
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1985
1985
Five hundred four outpatients suffering from a major depressive episode were randomly assigned to receive either amitriptyline… (More)
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1984
1984
Sixty patients with chronic pain of the low back or cervical spine concomitant with clinical depression were studied in a 6-week… (More)
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