Double-Strand Break Repair Protein MRE11A

Known as: Meiotic Recombination 11 Homolog A, MRE11 Homolog A, Endo/Exonuclease Mre11 
Double-strand break repair protein MRE11A (708 aa, ~81 kDa) is encoded by the human MRE11A gene. This protein plays a role in the mediation of DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
01220052017

Papers overview

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Review
2018
Review
2018
Genomic instability in disease and its fidelity in health depend on the DNA damage response (DDR), regulated in part from the… (More)
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2017
2017
The interaction between the meiotic recombination 11 homolog A (MRE11) oncoprotein and breast cancer recurrence status remains… (More)
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2016
2016
The innate immune system is an integral part of the host response to invading pathogens and endogenous danger signals. Pattern… (More)
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2015
2015
Etoposide (ETO), a drug used for the treatment of human tumors, is associated with the development of secondary malignancies… (More)
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2014
2014
Repair of DNA double strand breaks (DSBs) is influenced by the chemical complexity of the lesion. Clustered lesions (complex DSBs… (More)
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Highly Cited
2013
Highly Cited
2013
Microhomology-mediated end joining (MMEJ) is a major pathway for Ku-independent alternative nonhomologous end joining, which… (More)
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Highly Cited
2013
Highly Cited
2013
Double-stranded DNA (dsDNA) derived from pathogen- or host-damaged cells triggers innate immune responses when exposed to… (More)
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2011
2011
Gene expression is suppressed by DNA methylation. The goal of this study was to identify genes whose CpG site methylation and… (More)
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2005
2005
AIM The genes were divided into seven categories according to biological function; apoptosis-related, immune response-related… (More)
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2005
2005
re11–Rad50–Nbs1 (MRN) complex involvement in nonhomologous end joining (NHEJ) is controversial. The MRN complex is required for… (More)
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